Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
Cell entry by SARS-CoV-2
Severe acute respiratory syndrome virus 2 (SARS-CoV-2) invades host cells by interacting
with receptors/coreceptors, as well as with other cofactors, via its spike (S) protein that …
with receptors/coreceptors, as well as with other cofactors, via its spike (S) protein that …
Dysregulation of cell signaling by SARS-CoV-2
Pathogens usurp host pathways to generate a permissive environment for their propagation.
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …
Cell entry mechanisms of SARS-CoV-2
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) is
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
Can SARS-CoV-2 virus use multiple receptors to enter host cells?
LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …
SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that
has gained global attention owing to its ability to provoke community and health-care …
has gained global attention owing to its ability to provoke community and health-care …
Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2
Up to date, effective antivirals have not been widely available for treating COVID-19. In this
study, we identify a dual-functional cross-linking peptide 8P9R which can inhibit the two …
study, we identify a dual-functional cross-linking peptide 8P9R which can inhibit the two …
Targeted therapy strategies against SARS‐CoV‐2 cell entry mechanisms: a systematic review of in vitro and in vivo studies
S Seyedpour, B Khodaei, AH Loghman… - Journal of Cellular …, 2021 - Wiley Online Library
Due to the rapidly spreading of novel coronavirus disease (COVID‐19) worldwide, there is
an urgent need to develop efficient vaccines and specific antiviral treatments. Pathways of …
an urgent need to develop efficient vaccines and specific antiviral treatments. Pathways of …
Metalloproteinase-dependent and TMPRSS2-independent cell surface entry pathway of SARS-CoV-2 requires the furin cleavage site and the S2 domain of spike …
M Yamamoto, J Gohda, A Kobayashi, K Tomita… - Mbio, 2022 - Am Soc Microbiol
The ongoing global vaccination program to prevent SARS-CoV-2 infection, the causative
agent of COVID-19, has had significant success. However, recently, virus variants that can …
agent of COVID-19, has had significant success. However, recently, virus variants that can …
Structural and functional modelling of SARS-CoV-2 entry in animal models
SARS-CoV-2 is the novel coronavirus responsible for the outbreak of COVID-19, a disease
that has spread to over 100 countries and, as of the 26th July 2020, has infected over 16 …
that has spread to over 100 countries and, as of the 26th July 2020, has infected over 16 …
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