Role of F-box Protein Cdc4 in Fungal Virulence and Sexual Reproduction of Cryptococcus neoformans

T Wu, CL Fan, LT Han, YB Guo, TB Liu - Frontiers in Cellular and …, 2022 - frontiersin.org
Cryptococcus neoformans is an opportunistic yeast-like pathogen that mainly infects
immunocompromised individuals and causes fatal meningitis. Sexual reproduction can …

The F-Box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans

TB Liu, Y Wang, S Stukes, Q Chen, A Casadevall… - Eukaryotic …, 2011 - Am Soc Microbiol
Cryptococcus neoformans is the leading cause of fungal meningitis in immunocomprised
populations. Although extensive studies have been conducted on signal transduction …

The Cys2His2 zinc finger protein Zfp1 regulates sexual reproduction and virulence in Cryptococcus neoformans

CL Fan, LT Han, ST Jiang, AN Chang, ZY Zhou… - Fungal Genetics and …, 2019 - Elsevier
Cryptococcus neoformans is a ubiquitous yeast pathogen that often infects the human
central nervous system (CNS) to cause meningitis in immunocompromised individuals …

A cyclin protein governs the infectious and sexual life cycles of Cryptococcus neoformans

P Hu, L Liu, W Ke, X Tian, L Wang - Science China Life Sciences, 2021 - Springer
Cell cycle is a fundamental process underlying growth and development in evolutionarily
diverse organisms, including fungi. In human fungal pathogens, cell cycle control generally …

The Role of Oxidoreductase-Like Protein Olp1 in Sexual Reproduction and Virulence of Cryptococcus neoformans

QK Yu, LT Han, YJ Wu, TB Liu - Microorganisms, 2020 - mdpi.com
Cryptococcus neoformans is a basidiomycete human fungal pathogen causing lethal
meningoencephalitis, mainly in immunocompromised patients. Oxidoreductases are a class …

Phenotypic characterization of HAM1, a novel mating regulator of the fungal pathogen Cryptococcus neoformans

E Arsenault Yee, RL Ross… - Microbiology …, 2024 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen responsible for> 200,000 yearly cases with
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …

Autophagy Regulates Fungal Virulence and Sexual Reproduction in Cryptococcus neoformans

ST Jiang, AN Chang, LT Han, JS Guo… - Frontiers in Cell and …, 2020 - frontiersin.org
Autophagy (macroautophagy) is an evolutionarily conserved degradation pathway involved
in bulk degradation of cytoplasmic organelles, old protein, and other macromolecules and …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

The Link between Morphotype Transition and Virulence in Cryptococcus neoformans

L Wang, B Zhai, X Lin - PLoS pathogens, 2012 - journals.plos.org
Cryptococcus neoformans is a ubiquitous human fungal pathogen. This pathogen can
undergo morphotype transition between the yeast and the filamentous form and such …

Cryptococcus neoformans: Sex, morphogenesis, and virulence

Y Zhao, X Lin - Infection, Genetics and Evolution, 2021 - Elsevier
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis
mainly in immunocompromised individuals. Different morphotypes enable this …