[HTML][HTML] Bioinformatics for marine products: An overview of resources, bottlenecks, and perspectives

L Ambrosino, M Tangherlini, C Colantuono, A Esposito… - Marine drugs, 2019 - mdpi.com
The sea represents a major source of biodiversity. It exhibits many different ecosystems in a
huge variety of environmental conditions where marine organisms have evolved with …

[HTML][HTML] Omics for bioprospecting and drug discovery from bacteria and microalgae

R Maghembe, D Damian, A Makaranga, SS Nyandoro… - Antibiotics, 2020 - mdpi.com
“Omics” represent a combinatorial approach to high-throughput analysis of biological
entities for various purposes. It broadly encompasses genomics, transcriptomics …

A critical review of machine-learning for “multi-omics” marine metabolite datasets

J Manochkumar, AK Cherukuri, RS Kumar… - Computers in Biology …, 2023 - Elsevier
During the last decade, genomic, transcriptomic, proteomic, metabolomic, and other omics
datasets have been generated for a wide range of marine organisms, and even more are …

Introducing genomics, proteomics and metabolomics in marine ecology

SC Johnson, HI Browman, GE Hoffmann, SP Place… - Mar Ecol Prog …, 2007 - int-res.com
Introducing genomics, proteomics and metabolomics in marine ecology OPEN ACCESS
MARINE ECOLOGY PROGRESS SERIES Mar Ecol Prog Ser Vol. 332: 247–248, 2007 Published …

[HTML][HTML] Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds

J Rocha-Martin, C Harrington, ADW Dobson, F O'Gara - Marine drugs, 2014 - mdpi.com
Marine microorganisms continue to be a source of structurally and biologically novel
compounds with potential use in the biotechnology industry. The unique physiochemical …

New and emerging analytical techniques for marine biotechnology

JG Burgess - Current opinion in biotechnology, 2012 - Elsevier
Marine biotechnology is the industrial, medical or environmental application of biological
resources from the sea. Since the marine environment is the most biologically and …

[HTML][HTML] Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism

J Kennedy, B Flemer, SA Jackson, DPH Lejon… - Marine drugs, 2010 - mdpi.com
The marine environment is extremely diverse, with huge variations in pressure and
temperature. Nevertheless, life, especially microbial life, thrives throughout the marine …

[HTML][HTML] Global analysis of the biosynthetic chemical space of marine prokaryotes

B Wei, GA Hu, ZY Zhou, WC Yu, AQ Du, CL Yang… - Microbiome, 2023 - Springer
Background Marine prokaryotes are a rich source of novel bioactive secondary metabolites
for drug discovery. Recent genome mining studies have revealed their great potential to bio …

[HTML][HTML] Metabolomics and marine biotechnology: coupling metabolite profiling and organism biology for the discovery of new compounds

M Reverter, S Rohde, C Parchemin… - Frontiers in Marine …, 2020 - frontiersin.org
The high diversity of marine natural products represents promising opportunities for drug
discovery, an important area in marine biotechnology. Within this context, high-throughput …

[HTML][HTML] Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates

M Trindade, LJ Van Zyl, J Navarro-Fernández… - Frontiers in …, 2015 - frontiersin.org
Microbial natural products exhibit immense structural diversity and complexity and have
captured the attention of researchers for several decades. They have been explored for a …