A Bi‐Layer Hydrogel Cardiac Patch Made of Recombinant Functional Proteins

X Jiang, T Feng, B An, S Ren, J Meng, K Li… - Advanced …, 2022 - Wiley Online Library
The development of minimally invasive cardiac patches, either as hemostatic dressing or
treating myocardial infarction, is of clinical significance but remains a major challenge …

[HTML][HTML] Three-dimensionally printed hydrogel cardiac patch for infarct regeneration based on natural polysaccharides

J Loureiro, SP Miguel, V Galván-Chacón, D Patrocinio… - Polymers, 2023 - mdpi.com
Myocardial infarction is one of the more common cardiovascular diseases, and remains the
leading cause of death, globally. Hydrogels (namely, those using natural polymers) provide …

[HTML][HTML] Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

[HTML][HTML] Hydrogels for cardiac tissue engineering

G Camci-Unal, N Annabi, MR Dokmeci, R Liao… - NPG Asia …, 2014 - nature.com
Cardiac failure is a critical condition that results in life-threatening consequences. Due to a
limited number of organ donors, tissue engineering has emerged to generate functional …

Engineered biomaterials for heart disease

L Stapleton, Y Zhu, YJ Woo, E Appel - Current opinion in biotechnology, 2020 - Elsevier
Ischemic heart disease is the most common type of heart disease, responsible for roughly 10
million deaths worldwide annually. While standard clinical interventions have resulted in …

[HTML][HTML] Enzyme-responsive progelator cyclic peptides for minimally invasive delivery to the heart post-myocardial infarction

AS Carlini, R Gaetani, RL Braden, C Luo… - Nature …, 2019 - nature.com
Injectable biopolymer hydrogels have gained attention for use as scaffolds to promote
cardiac function and prevent negative left ventricular (LV) remodeling post-myocardial …

Highly elastic micropatterned hydrogel for engineering functional cardiac tissue

N Annabi, K Tsang, SM Mithieux… - Advanced functional …, 2013 - Wiley Online Library
Heart failure is a major international health issue. Myocardial mass loss and lack of
contractility are precursors to heart failure. Surgical demand for effective myocardial repair is …

A bioresorbable biomaterial carrier and passive stabilization device to improve heart function post-myocardial infarction

EB Dolan, B Hofmann, MH de Vaal, G Bellavia… - Materials science and …, 2019 - Elsevier
The limited regenerative capacity of the heart after a myocardial infarct results in remodeling
processes that can progress to congestive heart failure (CHF). Several strategies including …

Fabrication of hydrogel materials for biomedical applications

JM Yang, OS Olanrele, X Zhang, CC Hsu - Novel Biomaterials for …, 2018 - Springer
Hydrogels are three-dimensional hydrophilic polymeric networks that can be made from a
wide range of natural and synthetic polymers. This review discusses recent advanced …

[HTML][HTML] Hydrogels for cardiac tissue engineering

Z Li, J Guan - Polymers, 2011 - mdpi.com
Cardiac tissue regeneration is an integrated process involving both cells and supporting
matrix. Cardiomyocytes and stem cells are utilized to regenerate cardiac tissue. Hydrogels …