Decellularized bone matrix/oleoyl chitosan derived supramolecular injectable hydrogel promotes efficient bone integration

S Datta, AP Rameshbabu, K Bankoti, M Roy… - Materials Science and …, 2021 - Elsevier
Hydrogels derived from decellularized extracellular matrix (ECM) have been widely used as
a bioactive matrix for facilitating functional bone tissue regeneration. However, its poor …

A dual synergistic effect of titanium and curcumin co-embedded on extracellular matrix hydrogels of decellularized bone: Potential application in osteoblastic …

H Amirazad, A Baradar Khoshfetrat… - Journal of Biomaterials …, 2023 - Taylor & Francis
This research aims to design and fabricate a novel hydrogel-based composite as a
functional biomimetic and biocompatible scaffold for amended osteoblastic differentiation of …

A sodium alginate/carboxymethyl chitosan dual-crosslinked injectable hydrogel scaffold with tunable softness/hardness for bone regeneration

H Wang, J Yang, W Tian, K Peng, Y Xue, H Zhao… - International Journal of …, 2024 - Elsevier
Recently, injectable dual-crosslinked (DC) hydrogel scaffolds have attracted many attentions
as a class of excellent bone regeneration biomaterials with in-situ tunable functions …

Bioactive composite hydrogels as 3D mesenchymal stem cell encapsulation environment for bone tissue engineering: in vitro and in vivo studies

MT Vurat, M Parmaksiz, AE Elçin… - Journal of Biomedical …, 2023 - Wiley Online Library
Although decellularized bone matrix (DBM) has often been used in scaffold form for
osteogenic applications, its use as a stem cell encapsulation matrix adaptable to surgical …

In situ forming alginate/gelatin hydrogel scaffold through Schiff base reaction embedded with curcumin-loaded chitosan microspheres for bone tissue regeneration

N Amiryaghoubi, M Fathi, A Safary… - International Journal of …, 2024 - Elsevier
In this study, we developed a biocompatible composite hydrogel that incorporates
microspheres. This was achieved using a Schiff base reaction, which combines the amino …

Synergistic interplay between human MSCs and HUVECs in 3D spheroids laden in collagen/fibrin hydrogels for bone tissue engineering

DN Heo, M Hospodiuk, IT Ozbolat - Acta biomaterialia, 2019 - Elsevier
Stem cell encapsulation in hydrogels has been widely employed in tissue engineering,
regenerative medicine, organ-on-a-chip devices and gene delivery; however, fabrication of …

Injectable hydrogel delivering bone morphogenetic protein-2, vascular endothelial growth factor, and adipose-derived stem cells for vascularized bone tissue …

T Wang, S Guo, H Zhang, Y Chen, Y Cai - Journal of Drug Delivery Science …, 2020 - Elsevier
We aimed to evaluate the integration of stem cells with injectable microspheres loaded with
growth factors using a chitosan (CS) scaffold to promote healthy bone regeneration. We …

Hydroxyethyl chitosan-reinforced polyvinyl alcohol/biphasic calcium phosphate hydrogels for bone regeneration

L Nie, Y Deng, P Li, R Hou, A Shavandi, S Yang - Acs Omega, 2020 - ACS Publications
Fabrication of reinforced scaffolds for bone regeneration remains a significant challenge.
The weak mechanical properties of the chitosan (CS)-based composite scaffold hindered its …

A pH-triggered, self-assembled, and bioprintable hybrid hydrogel scaffold for mesenchymal stem cell based bone tissue engineering

C Zhao, NT Qazvini, M Sadati, Z Zeng… - … applied materials & …, 2019 - ACS Publications
Effective bone tissue engineering can restore bone and skeletal functions that are impaired
by traumas and/or certain medical conditions. Bone is a complex tissue and functions …

Injectable polysaccharide hydrogel embedded with hydroxyapatite and calcium carbonate for drug delivery and bone tissue engineering

B Ren, X Chen, S Du, Y Ma, H Chen, G Yuan… - International journal of …, 2018 - Elsevier
To meet the progressive requirements for bone regeneration purpose, injectable hydrogels
have attracted increasing attention in tissue regeneration and local drug delivery …