Statins and renin-angiotensin system inhibitor combination treatment to prevent cardiovascular disease

HY Lee, I Sakuma, SH Ihm, CW Goh, KK Koh - Circulation Journal, 2014 - jstage.jst.go.jp
282 LEE HY et al. comes, 15 recently published hypertension guidelines state that diuretics,
β-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors (ACEIs) and …

Combination of statin plus renin angiotensin system inhibition for the prevention or the treatment of atherosclerotic cardiovascular disease

VG Athyros, N Katsiki, A Karagiannis… - Current …, 2014 - ingentaconnect.com
Statins effectively reduce cardiovascular disease (CVD) morbidity and mortality. However,
even after low-density lipoprotein cholesterol goal attainment there is a residual CVD risk …

Statins, the renin–angiotensin–aldosterone system and hypertension–a tale of another beneficial effect of statins

A Drapala, M Sikora, M Ufnal - Journal of the Renin …, 2014 - journals.sagepub.com
Background: Statins, a class of lipid lowering drugs, decrease mortality associated with
cardiovascular events. As hypercholesterolemia is often accompanied by hypertension, a …

Renin-angiotensin system antagonism and lipid-lowering therapy in cardiovascular risk management

JR Chiong, AB Miller - Journal of the Renin-Angiotensin …, 2002 - journals.sagepub.com
The renin-angiotensin system (RAS) and dyslipidaemia have been shown to be involved in
the genesis and progression of atherosclerosis. Manipulation of the RAS has been effective …

Combined antihypertensive and statin therapy for the prevention of cardiovascular events in patients with hypertension without complications: protocol for a systematic …

Y Wang, ZM Kuang, SJ Feng, L Jiang, QX Chen… - BMJ open, 2018 - bmjopen.bmj.com
Introduction High blood pressure (BP) affects over 40% of adults over the age of 25
worldwide and is the leading global risk factor for death or disability. Hypertension is also …

Comparison of cardiovascular events in patients with angiographically documented coronary narrowing with combined renin-angiotensin system inhibitor plus statin …

M Fujita, T Yamazaki, D Hayashi, T Kohro… - The American journal of …, 2007 - Elsevier
Statins and renin-angiotensin system (RAS) inhibitors are 2 classes of drugs prescribed
frequently in clinical practice that may have pleiotropic effects in addition to cholesterol …

Renin–angiotensin system inhibitor and statins combination therapeutics–what have we learnt?

KK Koh, I Sakuma, T Hayashi, SH Kim… - Expert Opinion on …, 2015 - Taylor & Francis
Hypercholesterolemia and hypertension are the most common risk factors for cardiovascular
disease (CVD). Updated guidelines emphasize target reduction of overall cardiovascular …

The statins in preventive cardiology

D Steinberg - New England Journal of Medicine, 2008 - Mass Medical Soc
The Statins in Preventive Cardiology | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Pleiotropic effects of statins in atherosclerosis and diabetes

S Bellosta, N Ferri, L Arnaboldi, F Bernini - Diabetes care, 2000 - search.proquest.com
RESULTS—Fluvastatin. simvastatin, lovastatin, atorvastatin, and cerivastatin, but not
pravastatin, dose—dependently decrease smooth muscle cell (SMC) migration and …

The role of renin–angiotensin–aldosterone system‐based therapy in diabetes prevention and cardiovascular and renal protection

H Abuissa, J O'Keefe Jr - Diabetes, Obesity and Metabolism, 2008 - Wiley Online Library
Hypertension increases the risk of type 2 diabetes mellitus (T2DM) and cardiovascular
disease. In addition to lowering blood pressure, blockade of the renin–angiotensin …