ROS/RNS and base dual activatable merocyanine‐based NIR‐II fluorescent molecular probe for in vivo biosensing

X Zhang, Y Chen, H He, S Wang, Z Lei… - Angewandte …, 2021 - Wiley Online Library
Inflammation usually results in high‐level reactive oxygen species (ROS) and reactive
nitrogen species (RNS) not only in acidic tissue but also in alkaline tissue. However …

Near‐infrared chemiluminescent reporters for in vivo imaging of reactive oxygen and nitrogen species in kidneys

J Huang, J Huang, P Cheng, Y Jiang… - Advanced Functional …, 2020 - Wiley Online Library
Despite the superior sensitivity of chemiluminescence over fluorescence, most
chemiluminescence reporters only emit visible light, and have low water solubility, making …

Engineering of reversible NIR‐II redox‐responsive fluorescent probes for imaging of inflammation in vivo

L He, LH He, S Xu, TB Ren, XX Zhang… - Angewandte …, 2022 - Wiley Online Library
The second near‐infrared (NIR‐II) fluorescent imaging shows great potential for deep tissue
analysis at high resolution in living body owing to low background autofluorescence and …

Polymethine molecular platform for ratiometric fluorescent probes in the second near-infrared window

Q Lan, P Yu, K Yan, X Li, F Zhang… - Journal of the American …, 2022 - ACS Publications
Visualizing biomolecules such as enzymes in the deep tissue of living organisms via
molecular ratiometric fluorescent probes in the second near-infrared window (NIR-II) with a …

Development and application of a near-infrared fluorescence probe for oxidative stress based on differential reactivity of linked cyanine dyes

D Oushiki, H Kojima, T Terai, M Arita… - Journal of the …, 2010 - ACS Publications
Reactive oxygen species (ROS) operate as signaling molecules under various physiological
conditions, and overproduction of ROS is involved in the pathogenesis of many diseases …

Small molecule fluorescent probes for the detection of reactive nitrogen species in biological systems

Y Zhou, X Yang, S Xu, J Li, W Wang, M Yan - Coordination Chemistry …, 2023 - Elsevier
Reactive nitrogen species (RNS) as a class of vital reactive molecules, are essential for
maintaining homeostasis. Among RNS, nitric oxide (NO or NO.), peroxynitrite anion (ONOO …

Near-infrared fluorescence probe with a large stokes shift for visualizing hydrogen peroxide in ulcerative colitis mice

WX Wang, WL Jiang, Y Liu, Y Li, J Zhang… - Sensors and Actuators B …, 2020 - Elsevier
Ulcerative colitis (UC), as the main inflammatory disease in the colon, is regarded as one of
the most refractory diseases by World Health Organization. Hydrogen peroxide (H 2 O 2) is a …

NIRII‐HDs: A Versatile Platform for Developing Activatable NIR‐II Fluorogenic Probes for Reliable In Vivo Analyte Sensing

Z Qin, TB Ren, H Zhou, X Zhang, L He… - Angewandte Chemie …, 2022 - Wiley Online Library
Small‐molecule‐based second near‐infrared (NIR‐II) activatable fluorescent probes can
potentially provide a high target‐to‐background ratio and deep tissue penetration. However …

BODIPY-based fluorescent probe for dual-channel detection of nitric oxide and glutathione: visualization of cross-talk in living cells

XX Chen, LY Niu, N Shao, QZ Yang - Analytical chemistry, 2019 - ACS Publications
Nitric oxide (NO) and glutathione (GSH) have interplaying roles in oxidant-antioxidant
balance. In this work, we developed the first example of a single fluorescent probe that …

Size‐Transformable Superoxide‐Triggered Nanoreporters for Crosstalk‐Free Dual Fluorescence/Chemiluminescence Imaging and Urinalysis in Living Mice

B Ruan, M Yu, Y Zhou, W Xu, Y Liu… - Angewandte Chemie …, 2023 - Wiley Online Library
Chemiluminescence imaging has been recognized as a valuable tool for ultrasensitive
detection of physio‐pathological events through elimination of background …