Estimating the lowest detectable dose of ionizing radiation by the cytokinesis-block micronucleus assay
JD Tucker, M Vadapalli, MC Joiner… - Radiation …, 2013 - meridian.allenpress.com
The frequency of binucleated cells containing one or more micronuclei (MNBN cells) in
cytokinesis-blocked peripheral blood lymphocytes can be used to determine whether a …
cytokinesis-blocked peripheral blood lymphocytes can be used to determine whether a …
Development of a high-throughput and miniaturized cytokinesis-block micronucleus assay for use as a biological dosimetry population triage tool
SW Lue, M Repin, R Mahnke… - Radiation …, 2015 - meridian.allenpress.com
Biodosimetry is an essential tool for providing timely assessments of radiation exposure. For
a large mass-casualty event involving exposure to ionizing radiation, it is of utmost …
a large mass-casualty event involving exposure to ionizing radiation, it is of utmost …
Validation of the cytokinesis-block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry
MA Rodrigues, LA Beaton-Green, RC Wilkins - Health Physics, 2016 - journals.lww.com
The cytokinesis-block micronucleus assay can be employed in triage radiation biodosimetry
to determine the dose of radiation to an exposed individual by quantifying the frequency of …
to determine the dose of radiation to an exposed individual by quantifying the frequency of …
Laboratory intercomparison of the cytokinesis-block micronucleus assay
H Romm, S Barnard, H Boulay-Greene… - Radiation …, 2013 - meridian.allenpress.com
The focus of the study is an intercomparison of laboratories' dose-assessment performances
using the cytokinesis-block micronucleus (CBMN) assay as a diagnostic triage tool for …
using the cytokinesis-block micronucleus (CBMN) assay as a diagnostic triage tool for …
The cytokinesis-blocked micronucleus assay: dose–response calibration curve, background frequency in the population and dose estimation
An in vitro study of the dose responses of human peripheral blood lymphocytes was
conducted with the aim of creating calibrated dose–response curves for biodosimetry …
conducted with the aim of creating calibrated dose–response curves for biodosimetry …
Assay of micronuclei in peripheral blood lymphocytes as a biological indicator of radiation dose
B Sreedevi, BS Rao - Radiation protection dosimetry, 1994 - academic.oup.com
Chromosomal aberration analysis (CA) has regularly been used as a biological dosemeter
to evaluate suspected overexposures to ionising radiations. Recently, the micronucleus …
to evaluate suspected overexposures to ionising radiations. Recently, the micronucleus …
Validation of the cytokinesis-block micronucleus (CBMN) assay for use as a triage biological dosimetry tool
JP McNamee, FN Flegal, HB Greene… - Radiation protection …, 2009 - academic.oup.com
Traditionally, the dicentric chromosome assay (DCA) has been used to derive biological
dose estimates for unknown radiological exposures. While sensitive, this assay requires …
dose estimates for unknown radiological exposures. While sensitive, this assay requires …
Adaption of the cytokinesis-block micronucleus cytome assay for improved triage biodosimetry
C Beinke, M Port, A Riecke, CG Ruf… - Radiation …, 2016 - meridian.allenpress.com
The purpose of this work was to adapt a more advanced form of the cytokinesis-block
micronucleus (CBMN) cytome assay for triage biodosimetry in the event of a mass casualty …
micronucleus (CBMN) cytome assay for triage biodosimetry in the event of a mass casualty …
Monitoring of human exposure to radiation with the binucleated lymphocyte micronucleus assay.
JL He, HY Jin, LF Jin, SY Gao - Biomedical and Environmental …, 2000 - europepmc.org
The micronuclei (MN) of peripheral blood lymphocytes from radiation-exposed people were
monitored with the binucleated lymphocyte micronucleus assay (CBMN). MN rates in people …
monitored with the binucleated lymphocyte micronucleus assay (CBMN). MN rates in people …
Application of the Cytokinesis-Block Micronucleus Assay for High-Dose Exposures Using Imaging Flow Cytometry
EMHSC Sancheza, R Darwisha… - Cytogenet Genome …, 2023 - karger.com
The cytokinesis-block micronucleus assay is a wellestablished method to assess radiation-
induced genetic damage in human cells. This assay has been adapted to imaging flow …
induced genetic damage in human cells. This assay has been adapted to imaging flow …
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