Within the tumor microenvironment (TME), regulatory T cells (Tregs) play a key role in
suppressing anticancer immune responses; therefore, various strategies targeting Tregs are …

The adaptive immune system is modulated by an important subset of CD4+ T lymphocytes
called Treg cells that function in maintaining immune homeostasis by preventing excessive …

Recent evidence regarding the role of regulatory T cells (Treg) in tumor development has
suggested that the manipulation of Treg function selectively in the tumor microenvironment …

Overcoming the immunosuppressive tumour microenvironment is the major challenge
impeding cancer immunotherapy today. Regulatory T‐cells (Tregs) are prevalent in nearly …

Immunotherapies have revolutionized the landscape of cancer treatment. Regulatory T cells
(Tregs), as crucial components of the tumor immune environment, has great therapeutic …

Regulatory T cells (Tregs), possess a pivotal function in the maintenance of immune
homeostasis. The dysregulated activity of Tregs has been associated with the onset of …

With the broad application of cancer immunotherapies such as immune checkpoint inhibitors
in multiple cancer types, the immunological landscape in the tumor microenvironment (TME) …

The success of immunotherapy in oncology underscores the vital role of the immune system
in cancer development. Regulatory T cells (Tregs) maintain a fine balance between …

In contrast to conventional anti-tumor agents, nano-carriers allow co-delivery of distinct
drugs in a cell type-specific manner. So far, many nanodrug-based immunotherapeutic …

Although nonmalignant stromal cells facilitate tumor growth and can occupy up to 90% of a
solid tumor mass, better strategies to exploit these cells for improved cancer therapy are …