Resveratrol and the mitochondria: From triggering the intrinsic apoptotic pathway to inducing mitochondrial biogenesis, a mechanistic view
Background Mitochondria, the power plants of the cell, are known as a cross-road of
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …
different cellular signaling pathways. These cytoplasmic double-membraned organelles play …
Resveratrol and brain mitochondria: a review
FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol
M Ashrafizadeh, S Javanmardi… - Bioscience …, 2020 - portlandpress.com
Mitochondria are intracellular organelles with two distinct membranes, known as an outer
mitochondrial membrane and inner cell membrane. Originally, mitochondria have been …
mitochondrial membrane and inner cell membrane. Originally, mitochondria have been …
Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction
Most polyphenols can cross blood-brain barrier, therefore, they are widely utilized in the
treatment of various neurodegenerative diseases (ND). Resveratrol, a natural polyphenol …
treatment of various neurodegenerative diseases (ND). Resveratrol, a natural polyphenol …
Resveratrol directly binds to mitochondrial complex I and increases oxidative stress in brain mitochondria of aged mice
N Gueguen, V Desquiret-Dumas, G Leman, S Chupin… - PloS one, 2015 - journals.plos.org
Resveratrol is often described as a promising therapeutic molecule for numerous diseases,
especially in metabolic and neurodegenerative disorders. While the mechanism of action is …
especially in metabolic and neurodegenerative disorders. While the mechanism of action is …
Phytochemical modulators of mitochondria: The search for chemopreventive agents and supportive therapeutics
MM Grabacka, M Gawin, M Pierzchalska - Pharmaceuticals, 2014 - mdpi.com
Mitochondria are crucially important for maintaining not only the energy homeostasis, but the
proper cellular functions in a general sense. Impairment of mitochondrial functions is …
proper cellular functions in a general sense. Impairment of mitochondrial functions is …
Dietary polyphenols and mitochondrial function: role in health and disease
Mitochondria are cytoplasmic double-membraned organelles that are involved in a myriad of
key cellular regulatory processes. The loss of mitochondrial function is related to the …
key cellular regulatory processes. The loss of mitochondrial function is related to the …
[HTML][HTML] Resveratrol-mediated regulation of mitochondria biogenesis-associated pathways in neurodegenerative diseases: Molecular insights and potential …
Neurodegenerative disorders include different neurological conditions that affect nerve cells,
causing the progressive loss of their functions and ultimately leading to loss of mobility …
causing the progressive loss of their functions and ultimately leading to loss of mobility …
Natural compounds modulating mitochondrial functions
L Gibellini, E Bianchini, S De Biasi… - Evidence‐Based …, 2015 - Wiley Online Library
Mitochondria are organelles responsible for several crucial cell functions, including
respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main …
respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main …
Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment
W Sun, W Wang, J Kim, P Keng, S Yang… - Oxygen Transport to …, 2008 - Springer
Resveratrol, a phytoalexin found in the skin of grapes, is believed to have multiple
bioactivities including anti-cancer, anti-carcinogenesis and antiinflammatory. The …
bioactivities including anti-cancer, anti-carcinogenesis and antiinflammatory. The …