Genes associated with dasatinib sensitivity

DC Danila, HI Scher, M Fleisher - US Patent 10,113,200, 2018 - Google Patents
The invention relates to a method for the Cell Type specific labeling with Amino acid
Precursors (CTAP). In particular, the disclosed method permits the incorporation of stable …

Crystalline dasatinib process

S Rampalli, P Pothana, S Garbapu… - US Patent App. 15 …, 2016 - Google Patents
US20160264565A1 - Crystalline dasatinib process - Google Patents US20160264565A1 -
Crystalline dasatinib process - Google Patents Crystalline dasatinib process Download PDF Info …

Protein-targeted drug compound identification

M Manica, MR Martinez, J Born… - US Patent App. 17 …, 2020 - Google Patents
BACKGROUND [0002] The present invention relates generally to protein targeted drug
compound identification. Methods are pro vided for identifying drug compounds for targeting …

Identification of predictive markers of response to dasatinib in human colon cancer

DJ Slamon, RS Finn, J Dering, JR Hecht… - US Patent App. 12 …, 2011 - Google Patents
Methods and compositions are provided useful in the diagnosis, treatment and management
of cancers wherein cancer cells express certain polynucleotides and/or polypeptides that …

Methods to modulate lysine variant distribution

K Subramanian, MP Thiele, X Zeng, CF Wong… - US Patent …, 2017 - Google Patents
The instant invention relates to the field of protein production and purification, and in
particular to compositions and processes for controlling the distribution or amount of lysine …

Methods to modulate lysine variant distribution

K Subramanian, M Perez, X Zeng, CF Wong… - US Patent …, 2015 - Google Patents
The instant invention relates to the field of protein production and purification, and in
particular to compositions and processes for controlling the distribution or amount of lysine …

Use of non-canonical amino acids as metabolic markers for rapidly-dividing cells

D Tirrell, DC Dieterich, AJ Link… - US Patent App. 11 …, 2010 - Google Patents
The invention provides methods and reagents for metabolic labeling and detection of rapidly-
dividing cells, such as those found in tumors. The methods for labeling and/or detection are …

Method for judging sensibility to imatinib

R Ohno, T Tsuruo, Y Nakamura - US Patent App. 10/515,051, 2006 - Google Patents
FALLS CHURCH, VA 22040-0747 (US) A method of judging whether a patient is sensitive to
imatinib or not, in case where the patient is Suffering from 21) Appl. No.: 10/S15. 051 a …

Identification and quantification of a protein carrying an N-terminal polyhistidine affinity tag

T Burke, R Lowery, K Kleman-Leyer - US Patent App. 09/875,620, 2003 - Google Patents
BACKGROUND [0004] To realiZe the biomedical potential of human genome sequence and
expression data—an estimated 3,000 10,000 neW drug targets over the next ten years …

Highly parallel and sensitive method for identifying drugs and drug targets

R Davis, GN Giaever, D Shoemaker - US Patent 6,046,002, 2000 - Google Patents
The invention features methods for identifying gene products that mediate a phenotype,
such as drug resistance or sensitivity, as well as methods for identifying new bioactive …