A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties
Small-diameter synthetic vascular graft materials fail to match the patency of human tissue
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …
conduits used in vascular bypass surgery. The foreign surface retards endothelialization and …
Acellular vascular grafts generated from collagen and elastin analogs
Tissue-engineered vascular grafts require long fabrication times, in part due to the
requirement of cells from a variety of cell sources to produce a robust, load-bearing …
requirement of cells from a variety of cell sources to produce a robust, load-bearing …
Investigation of recombinant human elastin polypeptides as non-thrombogenic coatings
KA Woodhouse, P Klement, V Chen, MB Gorbet… - Biomaterials, 2004 - Elsevier
We investigated the use of a recombinant human elastin polypeptide as a coating on
synthetic materials with a view to determining if these polypeptides could improve the blood …
synthetic materials with a view to determining if these polypeptides could improve the blood …
Mechanical property characterization of electrospun recombinant human tropoelastin for vascular graft biomaterials
KA McKenna, MT Hinds, RC Sarao, PC Wu, CL Maslen… - Acta biomaterialia, 2012 - Elsevier
The development of vascular grafts has focused on finding a biomaterial that is non-
thrombogenic, minimizes intimal hyperplasia, matches the mechanical properties of native …
thrombogenic, minimizes intimal hyperplasia, matches the mechanical properties of native …
Fabricating organized elastin in vascular grafts
Z Wang, L Liu, SM Mithieux, AS Weiss - Trends in Biotechnology, 2021 - cell.com
Surgically bypassing or replacing a severely damaged artery using a biodegradable
synthetic vascular graft is a promising treatment that allows for the remodeling and …
synthetic vascular graft is a promising treatment that allows for the remodeling and …
Tri-layered vascular grafts composed of polycaprolactone, elastin, collagen, and silk: Optimization of graft properties
The purpose of this study was to create seamless, acellular, small diameter bioresorbable
arterial grafts that attempt to mimic the extracellular matrix and mechanical properties of …
arterial grafts that attempt to mimic the extracellular matrix and mechanical properties of …
In vivo performance of a phospholipid‐coated bioerodable elastomeric graft for small‐diameter vascular applications
There remains a great need for vascular substitutes for small‐diameter applications. The use
of an elastomeric biodegradable material, enabling acute antithrombogenicity and long …
of an elastomeric biodegradable material, enabling acute antithrombogenicity and long …
Biocompatibility and remodeling potential of pure arterial elastin and collagen scaffolds
DT Simionescu, Q Lu, Y Song, JS Lee, TN Rosenbalm… - Biomaterials, 2006 - Elsevier
Surgical therapy of cardiovascular disorders frequently requires replacement of diseased
tissues with prosthetic devices or grafts. In typical tissue engineering approaches, scaffolds …
tissues with prosthetic devices or grafts. In typical tissue engineering approaches, scaffolds …
The use of microfiber composites of elastin-like protein matrix reinforced with synthetic collagen in the design of vascular grafts
Collagen and elastin networks contribute to highly specialized biomechanical responses in
numerous tissues and species. Biomechanical properties such as modulus, elasticity, and …
numerous tissues and species. Biomechanical properties such as modulus, elasticity, and …
Elastin as a nonthrombogenic biomaterial
A Waterhouse, SG Wise, MKC Ng… - Tissue Engineering Part …, 2011 - liebertpub.com
Surface-induced thrombosis is a significant issue for artificial blood-contacting materials
used in the treatment of cardiovascular diseases. The development of biomaterials and …
used in the treatment of cardiovascular diseases. The development of biomaterials and …