The journey of a drug-carrier in the body: an anatomo-physiological perspective

N Bertrand, JC Leroux - Journal of controlled release, 2012 - Elsevier
Recent advances in chemistry and material sciences have witnessed the emergence of an
increasing number of novel and complex nanosized carriers for the delivery of drugs and …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Characterization of pharmaceutical nanocarriers: In vitro and in vivo studies

VL Gaikwad, PB Choudhari, NM Bhatia… - Nanomaterials for drug …, 2019 - Elsevier
Abstract Development of highly engineered and tailor-made pharmaceutical nanocarriers
with multifunctional properties is presently under consideration for modified drug delivery …

[图书][B] Colloidal carriers for controlled drug delivery and targeting: Modification, characterization and in vivo distribution

RH Müller - 1991 - books.google.com
Controlled drug delivery including drug targeting are topics attracting increasing attention.
They are of high interest for the delivery of drugs with major side effects (eg cytotoxics …

Targeted drug delivery—from magic bullet to nanomedicine: principles, challenges, and future perspectives

A Tewabe, A Abate, M Tamrie, A Seyfu… - Journal of …, 2021 - Taylor & Francis
Nanomedicine is an advanced version of Paul Ehrlich's “magic bullet” concept. Targeted
drug delivery is a system of specifying the drug moiety directly into its targeted body area …

Drug-loaded nanocarriers: passive targeting and crossing of biological barriers

JM Rabanel, V Aoun, I Elkin… - Current medicinal …, 2012 - ingentaconnect.com
Poor bioavailability and poor pharmacokinetic characteristics are some of the leading
causes of drug development failure. Therefore, poorly-soluble drugs, fragile proteins or …

Drug delivery: advancements and challenges

N Singh, A Joshi, AP Toor, G Verma - Nanostructures for drug delivery, 2017 - Elsevier
The enormous growth of nanotechnology paved ways for the development of advanced drug
delivery systems having ultraprecision and control over the release of drugs. Different …

Multifunctional nanocarriers

VP Torchilin - Advanced drug delivery reviews, 2006 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …

Therapeutic efficacy of nanoparticles and routes of administration

D Chenthamara, S Subramaniam… - Biomaterials …, 2019 - spj.science.org
In modern-day medicine, nanotechnology and nanoparticles are some of the indispensable
tools in disease monitoring and therapy. The term “nanomaterials” describes materials with …

Nanotechnology as a tool to overcome macromolecules delivery issues

LL Tundisi, JA Ataide, JSR Costa… - Colloids and Surfaces B …, 2023 - Elsevier
Nanocarriers can deliver drugs to specific organs or cells, potentially bridging the gap
between a drug's function and its interaction with biological systems such as human …