The role of extracellular matrix proteins in breast cancer

A Lepucki, K Orlińska, A Mielczarek-Palacz… - Journal of Clinical …, 2022 - mdpi.com
The extracellular matrix is a structure composed of many molecules, including fibrillar (types
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …

[HTML][HTML] Role of extracellular matrix in breast cancer development: a brief update

MK Jena, J Janjanam - F1000Research, 2018 - ncbi.nlm.nih.gov
Evidence is increasing on the crucial role of the extracellular matrix (ECM) in breast cancer
progression, invasion and metastasis with almost all mortality cases owing to metastasis …

[HTML][HTML] Extracellular matrix components in breast cancer progression and metastasis

T Oskarsson - The Breast, 2013 - Elsevier
The extracellular matrix (ECM) is composed of highly variable and dynamic components that
regulate cell behavior. The protein composition and physical properties of the ECM govern …

The extracellular matrix in breast cancer

J Insua-Rodríguez, T Oskarsson - Advanced drug delivery reviews, 2016 - Elsevier
The extracellular matrix (ECM) is increasingly recognized as an important regulator in breast
cancer. ECM in breast cancer development features numerous changes in composition and …

Extracellular matrix in the tumor microenvironment and its impact on cancer therapy

E Henke, R Nandigama, S Ergün - Frontiers in molecular biosciences, 2020 - frontiersin.org
Solid tumors are complex organ-like structures that consist not only of tumor cells but also of
vasculature, extracellular matrix (ECM), stromal, and immune cells. Often, this tumor …

The extracellular matrix in breast cancer predicts prognosis through composition, splicing, and crosslinking

C Robertson - Experimental Cell Research, 2016 - Elsevier
The extracellular matrix in the healthy breast has an important tumor suppressive role,
whereas the abnormal ECM in tumors can promote aggressiveness, and has been linked to …

Extracellular matrix: emerging roles and potential therapeutic targets for breast cancer

Y Zhao, X Zheng, Y Zheng, Y Chen, W Fei… - Frontiers in …, 2021 - frontiersin.org
Increasing evidence shows that the extracellular matrix (ECM) is an important regulator of
breast cancer (BC). The ECM comprises of highly variable and dynamic components …

[HTML][HTML] Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progression

M Giussani, G Merlino, V Cappelletti… - Seminars in cancer …, 2015 - Elsevier
Several evidences support the concept that cancer development and progression are not
entirely cancer cell-autonomous processes, but may be influenced, and possibly driven, by …

The functional role of extracellular matrix proteins in cancer

NV Popova, M Jücker - Cancers, 2022 - mdpi.com
Simple Summary Extracellular matrix is a three-dimensional network of macromolecules that
provide structural and biochemical support to surrounding cells. Extracellular matrix plays a …

[HTML][HTML] The biomimetic extracellular matrix: a therapeutic tool for breast cancer research

M Tamayo-Angorrilla, JL de Andrés, G Jiménez… - Translational …, 2022 - Elsevier
Background: A deeper knowledge of the functional versatility and dynamic nature of the
ECM has improved the understanding of cancer biology. Translational Significance: This …