Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals

BM Zeglis, JL Houghton, MJ Evans… - Inorganic …, 2014 - ACS Publications
Over the past several decades, radionuclides have matured from largely esoteric and
experimental technologies to indispensible components of medical diagnostics. Driving this …

Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals

S Bhattacharyya, M Dixit - Dalton transactions, 2011 - pubs.rsc.org
Metallic radionuclides are the mainstay of both diagnostic and therapeutic
radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous …

Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions

V Carroll, DW Demoin, TJ Hoffman, SS Jurisson - Radiochimica acta, 2012 - degruyter.com
Radiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This
field of radiochemistry is multidisciplinary, involving radiometal production, separation of the …

A brief overview of metal complexes as nuclear imaging agents

DS MacPherson, K Fung, BE Cook… - Dalton …, 2019 - pubs.rsc.org
Metallic radionuclides have been instrumental in the field of nuclear imaging for over half a
century. While recent years have played witness to a dramatic rise in the use of radiometals …

Tumour targeting with radiometals for diagnosis and therapy

CF Ramogida, C Orvig - Chemical Communications, 2013 - pubs.rsc.org
Use of radiometals in nuclear oncology is a rapidly growing field and encompasses a broad
spectrum of radiotracers for imaging via PET (positron emission tomography) or SPECT …

99mTc: Labeling Chemistry and Labeled Compounds

R Alberto, U Abram - Handbook of nuclear chemistry, 2011 - ui.adsabs.harvard.edu
This chapter reviews the radiopharmaceutical chemistry of technetium related to the
synthesis of perfusion agents and to the labeling of receptor-binding biomolecules. To …

Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

[HTML][HTML] Bifunctional chelates for metal nuclides

MW Brechbiel - The quarterly journal of nuclear medicine and …, 2008 - ncbi.nlm.nih.gov
The use of “non-standard” metallic radionuclides continues to be an expanding field of
investigation. Radiolabeling small molecules, peptides, proteins, and up to nano-particles …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Emerging chelators for nuclear imaging

D Sneddon, B Cornelissen - Current Opinion in Chemical Biology, 2021 - Elsevier
Chelators are necessary in nuclear medicine imaging to direct an inorganic radionuclide, a
radiometal, to a desired target; unfortunately, there is no 'one-size-fits-all'chelator. As the …