Mesenchymal cells in colon cancer
V Koliaraki, CK Pallangyo, FR Greten, G Kollias - Gastroenterology, 2017 - Elsevier
Mesenchymal cells in the intestine comprise a variety of cell types of diverse origins,
functions, and molecular markers. They provide mechanical and structural support and have …
functions, and molecular markers. They provide mechanical and structural support and have …
[HTML][HTML] Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease
J Kinchen, HH Chen, K Parikh, A Antanaviciute… - Cell, 2018 - cell.com
Intestinal mesenchymal cells play essential roles in epithelial homeostasis, matrix
remodeling, immunity, and inflammation. But the extent of heterogeneity within the colonic …
remodeling, immunity, and inflammation. But the extent of heterogeneity within the colonic …
Mesenchymal stem cells promote formation of colorectal tumors in mice
KS Tsai, SH Yang, YP Lei, CC Tsai, HW Chen, CY Hsu… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Tumor-initiating cells are a subset of tumor cells with the ability to
form new tumors; however, they account for less than 0.001% of the cells in colorectal or …
form new tumors; however, they account for less than 0.001% of the cells in colorectal or …
[HTML][HTML] Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer
E Strating, MP Verhagen, E Wensink… - Frontiers in …, 2023 - frontiersin.org
Background Poor prognosis in colon cancer is associated with a high content of cancer-
associated fibroblasts (CAFs) and an immunosuppressive tumor microenvironment. The …
associated fibroblasts (CAFs) and an immunosuppressive tumor microenvironment. The …
Cancer-associated fibroblasts in gastrointestinal cancer
The tumour microenvironment, also termed the tumour stroma or tumour mesenchyme,
includes fibroblasts, immune cells, blood vessels and the extracellular matrix and …
includes fibroblasts, immune cells, blood vessels and the extracellular matrix and …
[HTML][HTML] Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling
Mesenchymal stem cells (MSCs) have been reported to localize in colorectal carcinomas,
and participate in the formation of the tumor microenvironment. They have recently been …
and participate in the formation of the tumor microenvironment. They have recently been …
Intestinal mesenchymal cells
IV Pinchuk, RC Mifflin, JI Saada, DW Powell - Current gastroenterology …, 2010 - Springer
The non–white blood cell mesenchymal elements of the intestinal lamina propria are the
myofibroblasts, fibroblasts, pericytes, stromal stem cells, muscularis mucosae, and the …
myofibroblasts, fibroblasts, pericytes, stromal stem cells, muscularis mucosae, and the …
[HTML][HTML] Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages
M Stadler, K Pudelko, A Biermeier, N Walterskirchen… - Cancer Letters, 2021 - Elsevier
Colorectal cancer (CRC) accounts for about 10% of cancer deaths worldwide. Colon
carcinogenesis is critically influenced by the tumor microenvironment. Cancer associated …
carcinogenesis is critically influenced by the tumor microenvironment. Cancer associated …
Gastrointestinal stem cells
Turnover of the epithelial cell lineages within the gastrointestinal tract is a constant process,
occurring every 2–7 days under normal homeostasis and increasing after damage. This …
occurring every 2–7 days under normal homeostasis and increasing after damage. This …
The origin and contribution of cancer-associated fibroblasts in colorectal carcinogenesis
Background & Aims Cancer-associated fibroblasts (CAFs) play an important role in
colorectal cancer (CRC) progression and predict poor prognosis in CRC patients. However …
colorectal cancer (CRC) progression and predict poor prognosis in CRC patients. However …