Obesity I: Overview and molecular and biochemical mechanisms

RH Lustig, D Collier, C Kassotis, TA Roepke… - Biochemical …, 2022 - Elsevier
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

[HTML][HTML] Obesity wars: molecular progress confronts an expanding epidemic

JS Flier - Cell, 2004 - cell.com
The worldwide prevalence of obesity is increasing at an alarming rate, with major adverse
consequences for human health. This" obesity epidemic" is paralleled by a rapid and …

An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight

S Theilade, MB Christensen, T Vilsbøll… - Diabetes, Obesity and …, 2021 - Wiley Online Library
Obesity is one of the biggest health challenges of the 21st century, already affecting close to
700 million people worldwide, debilitating and shortening lives and costing billions of …

Brain regulation of food intake and appetite: molecules and networks

C Broberger - Journal of internal medicine, 2005 - Wiley Online Library
In the clinic, obesity and anorexia constitute prevalent problems whose manifestations are
encountered in virtually every field of medicine. However, as the command centre for …

[HTML][HTML] Energy homeostasis, obesity and eating disorders: recent advances in endocrinology

SM Gale, VD Castracane, CS Mantzoros - The Journal of nutrition, 2004 - Elsevier
Health problems resulting from obesity could offset many of the recent health gains achieved
by modern medicine, and obesity may replace tobacco as the number one health risk for …

Endocrine disrupters as obesogens

F Grün, B Blumberg - Molecular and cellular endocrinology, 2009 - Elsevier
The recent dramatic rise in obesity rates is an alarming global health trend that consumes an
ever increasing portion of health care budgets in Western countries. The root cause of …

Obesity and appetite control

K Suzuki, CN Jayasena… - Journal of Diabetes …, 2012 - Wiley Online Library
Obesity is one of the major challenges to human health worldwide; however, there are
currently no effective pharmacological interventions for obesity. Recent studies have …

Minireview: the case for obesogens

F Grun, B Blumberg - Molecular Endocrinology, 2009 - academic.oup.com
Obesity and obesity-related disorders, such as type 2 diabetes, hypertension, and
cardiovascular disease, are epidemic in Western countries, particularly the United States …

[HTML][HTML] Molecular links between obesity and diabetes:“diabesity”

A Chadt, S Scherneck, HG Joost, H Al-Hasani - 2015 - europepmc.org
Severe obesity represents a major risk factor for the development of type 2 diabetes mellitus
(T2DM). Due to the strong association of obesity and diabetes, the term “diabesity” was …