A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution
A Maida, A Zota, KA Sjøberg… - The Journal of …, 2022 - Am Soc Clin Investig
Dietary protein intake is linked to an increased incidence of type 2 diabetes (T2D). Although
dietary protein dilution (DPD) can slow the progression of some aging-related disorders …
dietary protein dilution (DPD) can slow the progression of some aging-related disorders …
[HTML][HTML] Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
Low-protein diets promote metabolic health in humans and rodents. Despite evidence that
sex and genetic background are key factors in the response to diet, most protein intake …
sex and genetic background are key factors in the response to diet, most protein intake …
Long-term effects of dietary protein and branched-chain amino acids on metabolism and inflammation in mice
Aging is the main factor involved in the onset of degenerative diseases. Dietary protein
restriction has been shown to increase the lifespan of rodents and improve metabolic …
restriction has been shown to increase the lifespan of rodents and improve metabolic …
Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints
CM Hill, T Laeger, DC Albarado, DH McDougal… - Scientific reports, 2017 - nature.com
Dietary protein restriction increases adipose tissue uncoupling protein 1 (UCP1), energy
expenditure and food intake, and these effects require the metabolic hormone fibroblast …
expenditure and food intake, and these effects require the metabolic hormone fibroblast …
Low protein diets produce divergent effects on energy balance
Diets deficient in protein often increase food consumption, body weight and fat mass;
however, the underlying mechanisms remain poorly understood. We compared the effects of …
however, the underlying mechanisms remain poorly understood. We compared the effects of …
The protein source determines the potential of high protein diets to attenuate obesity development in C57BL/6J mice
abstract The notion that the obesogenic potential of high fat diets in rodents is attenuated
when the protein: carbohydrate ratio is increased is largely based on studies using casein or …
when the protein: carbohydrate ratio is increased is largely based on studies using casein or …
[PDF][PDF] Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARa and FGF21 in mice with hepatic ablation of brain-derived …
S Teillon, GA Calderon, M Rios - J Endocrinol, 2010 - academia.edu
Brain-derived neurotropic factor (BDNF) mediates many aspects of neuronal function, and
plays a chief role in the central regulation of energy balance. In the periphery, it is expressed …
plays a chief role in the central regulation of energy balance. In the periphery, it is expressed …
[HTML][HTML] Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine-and choline-deficient diet
N Tanaka, S Takahashi, Y Zhang, KW Krausz… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Abstract Fibroblast growth factor 21 (FGF21) is a modulator of energy homeostasis and is
increased in human nonalcoholic liver disease (NAFLD) and after feeding of methionine …
increased in human nonalcoholic liver disease (NAFLD) and after feeding of methionine …
[HTML][HTML] Clinical evidence and mechanisms of high-protein diet-induced weight loss
J Moon, G Koh - Journal of obesity & metabolic syndrome, 2020 - ncbi.nlm.nih.gov
Several clinical trials have found that consuming more protein than the recommended
dietary allowance not only reduces body weight (BW), but also enhances body composition …
dietary allowance not only reduces body weight (BW), but also enhances body composition …
The differential plasma proteome of obese and overweight individuals undergoing a nutritional weight loss and maintenance intervention
S Oller Moreno, O Cominetti… - PROTEOMICS …, 2018 - Wiley Online Library
Purpose The nutritional intervention program “DiOGenes” focuses on how obesity can be
prevented and treated from a dietary perspective. We generated differential plasma …
prevented and treated from a dietary perspective. We generated differential plasma …