[HTML][HTML] Incorporation of T-cell epitopes from tetanus and diphtheria toxoids into in-silico-designed hypoallergenic vaccine may enhance the protective immune …
Objective (s): New generation of allergy vaccines is capable of promoting the development
of protective IgG and blocking the functionality of allergen-specific IgE. We incorporated …
of protective IgG and blocking the functionality of allergen-specific IgE. We incorporated …
In silico Identification of Potential Peptides or Allergen Shot Candidates Against Aspergillus fumigatus
R Thakur, J Shankar - BioResearch open access, 2016 - liebertpub.com
Aspergillus fumigatus is capable of causing invasive aspergillosis or acute
bronchopulmonary aspergillosis, and the current situation is alarming. There are no vaccine …
bronchopulmonary aspergillosis, and the current situation is alarming. There are no vaccine …
Construction by artificial intelligence and immunovalidation of hypoallergenic mite allergen Der f 36 vaccine
QZ Qin, J Tang, CY Wang, ZQ Xu, M Tian - Frontiers in Immunology, 2024 - frontiersin.org
Background The house dust mite (HDM) is widely recognized as the most prevalent allergen
in allergic diseases. Allergen-specific immunotherapy (AIT) has been successfully …
in allergic diseases. Allergen-specific immunotherapy (AIT) has been successfully …
In silico rational design of a novel tetra-epitope tetanus vaccine with complete population coverage using developed immunoinformatics and surface epitope mapping …
S Bazmara, M Shadmani, A Ghasemnejad… - Medical …, 2019 - Elsevier
Presentation of many unwanted epitopes within tetanus toxoid vaccine to lymphocyte clones
may lead to production of many unwanted antibodies. Moreover an ideal vaccine must cover …
may lead to production of many unwanted antibodies. Moreover an ideal vaccine must cover …
In Silico Design of a New Epitope-Based Vaccine against Grass Group 1 Allergens
D Moten, T Batsalova, D Apostolova… - … in Respiratory Medicine, 2023 - mdpi.com
Highlights What are the main findings? A peptide consisting of 20 amino acids was
designed in silico as a grass pollen allergy vaccine. The epitope-based vaccine has been …
designed in silico as a grass pollen allergy vaccine. The epitope-based vaccine has been …
Designing Next-Generation Vaccines Against Common Pan-Allergens Using In Silico Approaches
Next-generation allergy vaccines refer to allergen-derived attenuated molecules that can
boost allergen-blocking IgG response. These IgG antibodies are specifically directed toward …
boost allergen-blocking IgG response. These IgG antibodies are specifically directed toward …
In Silico Design of Epitope-Based Allergy Vaccine Against Bellatella germanica Cockroach Allergens
Asthma is a chronic inflammatory airway disorder that is a subclass of IgE mediated
hypersensitivity. Cockroach allergy is one of the main reasons of asthma. German cockroach …
hypersensitivity. Cockroach allergy is one of the main reasons of asthma. German cockroach …
Designing an epitope vaccine against Dermatophagoides pteronyssinus: An in silico study
The house dust mite, Dermatophagoides pteronyssinus, is a major source of the inhaled
allergen Der p 1, which causes immunoglobulin E (IgE)-mediated hypersensitivity reactions …
allergen Der p 1, which causes immunoglobulin E (IgE)-mediated hypersensitivity reactions …
Immunoinformatics construction of B cell epitope-based hypoallergenic der f 34 vaccine for immunotherapy of house dust mite allergy
PY Yu, Y Zhu, LX Tan, ZQ Xu, C Lu… - International Journal of …, 2022 - Springer
House dust mites are one of the most important allergen sources worldwide and affect
approximately 50% of asthmatic patients. Allergen-specific immunotherapy (AIT) is the only …
approximately 50% of asthmatic patients. Allergen-specific immunotherapy (AIT) is the only …
[PDF][PDF] Immunoinformatics based vaccine design for Zea M 1 Pollen Allergen
Objective: Zea m1 is one of the most common aeroallergens, causing allergy. This pollen
allergen, present in maize, is responsible for type I hypersensitivity reaction. Despite having …
allergen, present in maize, is responsible for type I hypersensitivity reaction. Despite having …