Do sterols reduce proton and sodium leaks through lipid bilayers?

TH Haines - Progress in lipid research, 2001 - Elsevier
Proton and/or sodium electrochemical gradients are critical to energy handling at the plasma
membranes of all living cells. Sodium gradients are used for animal plasma membranes, all …

[HTML][HTML] Squalane is in the midplane of the lipid bilayer: implications for its function as a proton permeability barrier

T Hauß, S Dante, NA Dencher, TH Haines - Biochimica et Biophysica Acta …, 2002 - Elsevier
A recently proposed model for proton leakage across biological membranes [Prog. Lipid
Res. 40 (2001) 299] suggested that hydrocarbons specifically in the center of the lipid …

Anionic lipid headgroups as a proton-conducting pathway along the surface of membranes: a hypothesis.

TH Haines - Proceedings of the National Academy of …, 1983 - National Acad Sciences
Evidence has been gathering from several laboratories that protons in proton-pumping
membranes move along or within the bilayer rather than exchange with the bulk phase …

Proton permeation of lipid bilayers

DW Deamer - Journal of bioenergetics and biomembranes, 1987 - Springer
Proton permeation of the lipid bilayer barrier has two unique features. First, permeability
coefficients measured at neutral pH ranges are six to seven orders of magnitude greater …

Cholesterol and other membrane active sterols: from membrane evolution to “rafts”

Y Barenholz - Progress in lipid research, 2002 - Elsevier
The appearance of “membrane-active sterols” in biological membranes of eukaryocytes is
one of the major steps in membrane evolution. This is exemplified best by membrane-active …

Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol

Y Lange, TL Steck - Progress in lipid research, 2008 - Elsevier
We review evidence that sterols can form stoichiometric complexes with certain bilayer
phospholipids, and sphingomyelin in particular. These complexes appear to be the basis for …

Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation

BN Olsen, PH Schlesinger… - Journal of the American …, 2009 - ACS Publications
Cholesterol is essential for proper function and regulation of eukaryotic membranes, and
significant amounts of metabolic energy are dedicated to controlling cellular cholesterol …

Intracellular sterol transport and distribution

FR Maxfield, AK Menon - Current opinion in cell biology, 2006 - Elsevier
Sterols are important components of many biological membranes, and changes in sterol
levels can have dramatic effects on membrane properties. Sterols are transported rapidly …

Sterol, structure and membrane function

KE Bloch - Critical Reviews in Biochemistry, 1983 - Taylor & Francis
This review deals with sterol structure-function relationships in natural and artificial
membranes covering for the most part research carried out in this laboratory during the last 4 …

Distribution and functions of sterols and sphingolipids

JT Hannich, K Umebayashi… - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Sterols and sphingolipids are considered mainly eukaryotic lipids even though both are
present in some prokaryotes, with sphingolipids being more widespread than sterols. Both …