Gene therapy is a promising strategy for specific treatment of numerous gene-associated
human diseases by intentionally altering the gene expression in pathological cells. A …

Since the evolution of the concept of gene therapy, delivering therapeutic genes to the
diseased cells has been a major challenge. Although viral vectors have been shown to be …

Compared to conventional treatments, gene therapy offers a variety of advantages for
cancer treatment including high potency and specificity, low off-target toxicity, and delivery of …

Gene therapy, as therapeutic treatment to genetic or acquired diseases, is attracting much
interest in the research community, leading to noteworthy developments over the past two …

With the development of genomic technologies, the prospect for gene therapy has
progressed rapidly. The major challenge of gene delivery is to improve the transfection …

With the remarkable development of nanotechnology in recent years, new drug delivery
approaches based on the state‐of‐the‐art nanotechnology have been receiving significant …

Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

Biomedical application of nanotechnology is a rapidly developing area that raises new
prospect in the improvement of diagnosis and treatment of human diseases. The ability to …

Context The size of nanoparticles plays a pivotal role in determining the gene delivery
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …

Although the potential benefits of gene therapy for the treatment of acquired and inherited
genetic diseases have been demonstrated through preclinical studies, the results of human …