Τα ενδογενή κατιονικά αντιμικροβιακά πεπτίδια αποτελούν σημαντικούςπαράγοντες της
φυσικής ανοσίας σε όλα τα ζωικά είδη όπου έχουν βρεθείκαι μελετηθεί. Στα θηλαστικά …

OPINION ARTICLE published: 14 August 2012 doi: 10.3389/fimmu. 2012.00249 the six
conserved cysteine residues. They are composed of three antiparallel β-sheets and exhibit a …

Οι Defensins είναι μικρά, αντιμικροβιακά πεπτίδια (Anti-Microbial Peptides: AMP) τα οποία
μέσω των διάφορων αμυντικών μηχανισμών που συμμετέχουν, παρέχουν προστασία έναντι …

Conclusions Many lines of evidence support the theory that Paneth cell defensins are major
antimicrobials of the small intestine and key to innate immunity of this mucosal tissue. Given …

Human beta defensin 2 (HBD-2), the most recently discovered human defensin, has been
considered to work as a host defense substance against microbial infection. Using …

Human tuberculosis remains a huge global public health problem with an estimated 1/3rd of
the population being infected. Defensins are antibacterial cationic peptides produced by a …

Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

Naturally occurring antimicrobial cationic polypeptides play a major role in innate and
adaptive immunity. These polypeptides are found to be either linear and unstructured or …

Human defensins were originally identified as natural antimicrobial peptides that protect the
host from infections. More recently, novel biological functions of these peptides have been …

ABSTRACT β-Defensins are a family of small cationic peptides involved in the innate
response to microbial infection. Although their role in microbial killing is well established, the …