[PDF][PDF] Efficacy, tolerability and safety of nebivolol in patients with hypertension and diabetes: a post-marketing surveillance study

LM Van Bortel - Eur Rev Med Pharmacol Sci, 2010 - europeanreview.org
Background and Objectives: Hypertension is a widely prevalent con-dition of elevated blood
pressure (BP) and is the leading risk factor for the development of cardiovascular disease …

Long-term efficacy of nebivolol monotherapy in patients with hypertension

TJ Cleophas, I Grabowsky, MG Niemeyer… - Current therapeutic …, 2001 - Elsevier
Background: The antihypertensive activity of beta-blockers generally increases during the
first 6 to 8 weeks of treatment; however, no study has systematically assessed whether blood …

Comparison of Nebivolol monotherapy versus Nebivolol in combination with other antihypertensive therapies for the treatment of hypertension

V Papademetriou - The American journal of cardiology, 2009 - Elsevier
Nebivolol is a novel, β1-adrenergic receptor blocker with vasodilatory properties mediated
through the activation of the l-arginine/nitric oxide pathway. Short-term randomized clinical …

Efficacy and safety of nebivolol in hypertensive patients: a meta-analysis of randomized controlled trials

JY Liu, LN Guo, WZ Peng, Y Jiang… - Journal of …, 2020 - journals.sagepub.com
Purpose Our meta-analysis was undertaken to evaluate the efficacy and safety of nebivolol
compared with other second-generation β blockers for hypertensive patients. Methods We …

Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis

LM Van Bortel, F Fici, F Mascagni - American Journal of Cardiovascular …, 2008 - Springer
Background and objective Lowering BP to normal levels without quality of life deterioration
is the most important means of reducing cardiovascular risk. Recent studies have …

Blood pressure-lowering effect of nebivolol in hypertensive patients with type 2 diabetes mellitus: the YESTONO study

AC Schmidt, C Graf, K Brixius, J Scholze - Clinical drug investigation, 2007 - Springer
Background: Effective blood pressure (BP)-lowering therapy is regarded as the most
important intervention in diabetes mellitus. Nebivolol is commonly used for the treatment of …

A Randomized, Double‐Blind, Placebo‐Controlled Parallel‐Group Study to Assess the Efficacy and Safety of Nebivolol, a Novel β‐Blocker, in Patients With Mild to …

RJ Weiss, MA Weber, AA Carr… - The Journal of Clinical …, 2007 - Wiley Online Library
This double‐blind, multicenter, randomized placebo‐controlled study evaluated the
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …

[引用][C] Nebivolol in Hypertension: One-Year Treatment Data

G Sieben, L Van Nueten, J Symoens - Drug Investigation, 1991 - Springer
In order to evaluate the efficacy and tolerability of nebivolol during long term treatment of
outpatients with hypertension, 6 open multicentre studies are being carried out in 5 different …

Nebivolol: A third-generation β-blocker for hypertension

JWM Cheng - Clinical therapeutics, 2009 - Elsevier
Background: Nebivolol is a third-generation β1-selective β-blocker that is approved for the
treatment of hypertension. Objective: This article reviews the clinical pharmacology of …

Quality of life and efficacy of nebivolol in an open-label study in hypertensive patients. the QoLaN study

MP Hermans, O De Coster, L Seidel, A Albert… - Blood …, 2009 - Taylor & Francis
Background. Nebivolol is a highly selective β1-adrenoreceptor antagonist with vasodilating
properties. This study investigated its effect on quality of life (QoL) and blood pressure (BP) …