Potential molecular targeted therapy for unresectable hepatocellular carcinoma

S Kumar, AK Pandey - Current Oncology, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers,
representing a serious worldwide health concern. The recurrence incidence of …

[HTML][HTML] Advances of targeted therapy for hepatocellular carcinoma

M Niu, M Yi, N Li, K Wu, K Wu - Frontiers in Oncology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the common and fatal malignancies, which is a
significant global health problem. The clinical applicability of traditional surgery and other …

Combination of molecularly targeted therapies and immune checkpoint inhibitors in the new era of unresectable hepatocellular carcinoma treatment

ZL Liu, JH Liu, D Staiculescu… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Multikinase inhibitors (MKIs) have been the only first-line treatment for advanced
hepatocellular carcinoma (HCC) for more than a decade, until the approval of immune …

Targeted therapy for hepatocellular carcinoma: old and new opportunities

C Laface, P Fedele, FM Maselli, F Ambrogio, C Foti… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the most frequent primitive cancer of
the liver, accounting for 90% of all recorded cases. HCC is the third most common cause of …

Hepatocellular carcinoma: molecular mechanisms and targeted therapies

A Alqahtani, Z Khan, A Alloghbi, T S. Said Ahmed… - Medicina, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors
worldwide. HCC is a complex process that is associated with several etiological factors …

Advances in novel systemic therapies for advanced hepatocellular carcinoma

R Carloni, A Rizzo, A Cusmai, A Palloni… - Future Medicinal …, 2022 - Future Science
Hepatocellular carcinoma (HCC) represents the most frequent type of primary liver tumor.
Most HCC patients present with advanced disease at diagnosis and the recurrence rate after …

Current translational and clinical challenges in advanced hepatocellular carcinoma

M Frizziero, MG McNamara, A Lamarca… - Current Medicinal …, 2020 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a frequent and increasing cause of cancerrelated deaths
worldwide. Reversing this trend is complicated by the varied aetiological factors leading to …

Molecular therapies and precision medicine for hepatocellular carcinoma

JM Llovet, R Montal, D Sia, RS Finn - Nature reviews Clinical oncology, 2018 - nature.com
The global burden of hepatocellular carcinoma (HCC) is increasing and might soon surpass
an annual incidence of 1 million cases. Genomic studies have established the landscape of …

Molecularly targeted therapy for hepatocellular carcinoma from the basic and clinical aspects

S Arii - International journal of clinical oncology, 2010 - Springer
Although the diagnosis of and treatments for hepatocellular carcinoma (HCC) have
advanced remarkably in recent years, HCC is still one of the most common malignancies …

Evolving therapeutic landscape of advanced hepatocellular carcinoma

C Yang, H Zhang, L Zhang, AX Zhu… - Nature reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common solid malignancies worldwide.
A large proportion of patients with HCC are diagnosed at advanced stages and are only …