Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …

The 1, 4-benzodiazepine (BDZ) scaffold is of particular interest in drug design due to a
balanced ensemble of beneficial physicochemical properties including a semirigid and …

A novel green and efficient one-pot three-component synthesis of 2, 4-disubstituted-3 H-
benzo [b][1, 4] diazepines in excellent isolated yields has been reported. The methodology …

Benzodiazepines (BZDs) represent a class of privilege scaffold in the modern era of
medicinal chemistry as CNS active agents and BZD based drugs are used to treat different …

Condensation reactions of o-phenylenediamine and 2 equiv of acetone produce biaryl-
substituted 1, 5-benzodiazepines. The synthetic protocol shows general applicability since …

2-Substituted benzimidazoles and 3, 1, 5-benzoxadiazepines have been synthesized in
excellent yields in a single pot by cyclodehydration of N-acyl-1, 2-phenylenediamines and …

A simple and efficient synthetic route to 2, 3, 4, 5-tetrahydrobenzoxazepines and-
benzodiazepines bearing easily functionalizable appendages has been developed by ring …

Due to their widespread biological activities and favorable pharmacokinetic properties,
benzodiazepines were among the first classes of small molecules to be synthesized on solid …

2, 4-Di (hetero) aryl substituted 2, 3-dihydro 1, 5-benzoheteroazepines (hetero= NH, O, S)
can be readily sythesized in a one-pot process initiated by a coupling− isomerization …