Spectral-differential-based unmixing for multispectral photoacoustic imaging

T Hirasawa, RJ Iwatate, M Kamiya, S Okawa… - Applied Optics, 2018 - opg.optica.org
We propose the use of a spectral differential method (SDM) to emphasize the spectral peaks
of multispectral photoacoustic images. Because contrast agent signals have spectral peaks …

An automatic unmixing approach to detect tissue chromophores from multispectral photoacoustic imaging

V Grasso, J Holthof, J Jose - Sensors, 2020 - mdpi.com
Multispectral photoacoustic imaging has been widely explored as an emerging tool to
visualize and quantify tissue chromophores noninvasively. This modality can capture the …

[HTML][HTML] Optical wavelength selection for improved spectroscopic photoacoustic imaging

GP Luke, SY Nam, SY Emelianov - Photoacoustics, 2013 - Elsevier
Spectroscopic photoacoustic imaging has the potential to become a powerful tool that can
estimate distributions of optically absorbing chromophores in the body. We have developed …

Fast unmixing of multispectral optoacoustic data with vertex component analysis

XL Deán-Ben, NC Deliolanis, V Ntziachristos… - Optics and Lasers in …, 2014 - Elsevier
Multispectral optoacoustic tomography enhances the performance of single-wavelength
imaging in terms of sensitivity and selectivity in the measurement of the biodistribution of …

In vitro and in vivo multispectral photoacoustic imaging for the evaluation of chromophore concentration

A Dolet, R Ammanouil, V Petrilli, C Richard, P Tortoli… - Sensors, 2021 - mdpi.com
Multispectral photoacoustic imaging is a powerful noninvasive medical imaging technique
that provides access to functional information. In this study, a set of methods is proposed and …

Subband photoacoustic imaging for contrast improvement

PC Li, CW Wei, Y Sheu - Optics Express, 2008 - opg.optica.org
Contrast in photoacoustic imaging is primarily determined by optical absorption. This paper
proposes a subband imaging method to further enhance the image contrast. The method is …

Multispectral photoacoustic imaging of tumours in mice injected with an enzyme-activatable photoacoustic probe

T Hirasawa, RJ Iwatate, M Kamiya, S Okawa… - Journal of …, 2016 - iopscience.iop.org
Photoacoustic (PA) imaging offers depth-resolved images of optical absorbers with the
spatial resolution of ultrasound imaging. To enhance tumour contrast, tumour-specific …

Optimization of in vivo spectroscopic photoacoustic imaging by smart optical wavelength selection

GP Luke, SY Emelianov - Optics letters, 2014 - opg.optica.org
Spectroscopic photoacoustic (sPA) imaging is an emerging biomedical imaging modality
which can be used to simultaneously identify multiple optical absorbers in tissue. With …

Blind source unmixing in multi-spectral optoacoustic tomography

J Glatz, NC Deliolanis, A Buehler, D Razansky… - Optics express, 2011 - opg.optica.org
Multispectral optoacoustic (photoacoustic) tomography (MSOT) is a hybrid modality that can
image through several millimeters to centimeters of diffuse tissues, attaining resolutions …

Estimating relative chromophore concentrations from multiwavelength photoacoustic images using independent component analysis

L An, BT Cox - Journal of biomedical optics, 2018 - spiedigitallibrary.org
Independent component analysis (ICA) is an unmixing method based on a linear model. It
has previously been applied in in vivo multiwavelength photoacoustic imaging studies to …