Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: a review

H Huvenne, G Smagghe - Journal of insect physiology, 2010 - Elsevier
RNA interference already proved its usefulness in functional genomic research on insects,
but it also has considerable potential for the control of pest insects. For this purpose, the …

RNAi for insect control: current perspective and future challenges

R Katoch, A Sethi, N Thakur, LL Murdock - Applied biochemistry and …, 2013 - Springer
The research on the RNA interference (RNAi) for the control of insect pests has made
significant growth in recent years. The availability of the genomic sequences of insects has …

The mysteries of insect RNAi: A focus on dsRNA uptake and transport

AM Vélez, E Fishilevich - Pesticide biochemistry and physiology, 2018 - Elsevier
RNA interference (RNAi) is becoming a practical tool to control insect pests. Many mysteries
of how double-stranded RNA (dsRNA) is transported into, within, and between cells to …

Reduced stability and intracellular transport of dsRNA contribute to poor RNAi response in lepidopteran insects

JN Shukla, M Kalsi, A Sethi, KE Narva, E Fishilevich… - RNA biology, 2016 - Taylor & Francis
ABSTRACT RNA interference (RNAi) has become a widely used reverse genetic tool to
study gene function in eukaryotic organisms and is being developed as a technology for …

Delivery of dsRNA for RNAi in insects: an overview and future directions

N Yu, O Christiaens, J Liu, J Niu, K Cappelle… - Insect …, 2013 - Wiley Online Library
RNA interference (RNAi) refers to the process of exogenous double‐stranded RNA (dsRNA)
silencing the complementary endogenous messenger RNA. RNAi has been widely used in …

RNAi in insects: a revolution in fundamental research and pest control applications

O Christiaens, J Niu, C Nji Tizi Taning - Insects, 2020 - mdpi.com
In this editorial for the Special Issue on 'RNAi in insect pest control', three important
applications of RNA interference (RNAi) in insects are briefly discussed and linked to the …

Contributions of dsRNases to differential RNAi efficiencies between the injection and oral delivery of dsRNA in Locusta migratoria

H Song, Y Fan, J Zhang, AMW Cooper… - Pest Management …, 2019 - Wiley Online Library
BACKGROUND The efficiency of RNA interference (RNAi) varies considerably among
different insect species, and there is growing evidence to suggest that degradation of double …

The involvement of clathrin‐mediated endocytosis and two Sid‐1‐like transmembrane proteins in double‐stranded RNA uptake in the Colorado potato beetle midgut

K Cappelle, CFR de Oliveira… - Insect molecular …, 2016 - Wiley Online Library
RNA interference (RNAi) is a powerful tool in entomology and shows promise as a crop
protection strategy, but variability in its efficiency across different insect species limits its …

Molecular mechanisms influencing efficiency of RNA interference in insects

AMW Cooper, K Silver, J Zhang, Y Park… - Pest management …, 2019 - Wiley Online Library
RNA interference (RNAi) is an endogenous, sequence‐specific gene‐silencing mechanism
elicited by small RNA molecules. RNAi is a powerful reverse genetic tool, and is currently …

dsRNA uptake in plant pests and pathogens: insights into RNAi-based insect and fungal control technology

N Wytinck, CL Manchur, VH Li, S Whyard, MF Belmonte - Plants, 2020 - mdpi.com
Efforts to develop more environmentally friendly alternatives to traditional broad-spectrum
pesticides in agriculture have recently turned to RNA interference (RNAi) technology. With …