RNA methylation in inflammatory bowel disease

Y Ozato, T Hara, S Meng, H Sato, S Tatekawa… - Cancer …, 2024 - Wiley Online Library
RNA modifications, including the renowned m6A, have recently garnered significant
attention. This chemical alteration, present in mRNA, exerts a profound influence on protein …

The emerging clinical application of m6A RNA modification in inflammatory bowel disease and its associated colorectal cancer

X Xu, J Huang, DKW Ocansey, Y Xia… - Journal of …, 2021 - Taylor & Francis
Methylation, first proposed in DNAs, but later found in RNAs, serves as one of the most
widespread epigenetic modifications in eukaryotes, where N6-methyladenosine (m6A) …

Emerging roles of RNA methylation in gastrointestinal cancers

S Xie, W Chen, K Chen, Y Chang, F Yang, A Lin… - Cancer cell …, 2020 - Springer
RNA methylation has emerged as a fundamental process in epigenetic regulation.
Accumulating evidences indicate that RNA methylation is essential for many biological …

Epigenetic modification of m6A methylation: Regulatory factors, functions and mechanism in inflammatory bowel disease

Y Wang, C Chen, W Yan, Y Fu - The International Journal of Biochemistry & …, 2024 - Elsevier
Although the exact cause of inflammatory bowel disease (IBD) is still unknown, there is a lot
of evidence to support the notion that it results from a combination of environmental factors …

The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis

MB Uddin, Z Wang, C Yang - Molecular cancer, 2021 - Springer
The m 6 A RNA methylation is the most prevalent internal modification in mammalian
mRNAs which plays critical biological roles by regulating vital cellular processes …

Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers

D Ramasamy, M Thippannah, HRP Maharajan… - Molecular Biology …, 2024 - Springer
Abstract Background N6-methyladenosine (m6A) is a prevalent and crucial RNA methylation
modification that plays a significant role in various biological and pathological processes …

The role of m6A RNA methylation in human cancer

XY Chen, J Zhang, JS Zhu - Molecular cancer, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) is identified as the most common, abundant and
conserved internal transcriptional modification, especially within eukaryotic messenger …

The role of m6A RNA methylation in cancer metabolism

Y An, H Duan - Molecular cancer, 2022 - Springer
Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …

Dysregulation of m6A RNA methylation regulators in colorectal cancer: clinical implication as prognostic biomarkers and potential therapeutic targets

R Kandimalla, F Gao, C Ruan, M Hsieh, X Wang… - Cancer Research, 2018 - AACR
Purpose Among more than 100 known post-transcriptional modifications, N6-
Methyladenosine (m6A) represents the most prevalent internal modification in mammalian …

[HTML][HTML] Overview of the interplay between m6A methylation modification and non-coding RNA and their impact on tumor cells

Z Dou, XT Ma, MN Piao, JP Wang… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) is one of the most common internal modifications in
eukaryotic RNA. The presence of m6A on transcripts can affect a series of fundamental …