[HTML][HTML] Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants
CHS da Costa, CAB de Freitas, CN Alves… - Scientific Reports, 2022 - nature.com
The severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) variant Omicron
spread more rapid than the other variants of SARS-CoV-2 virus. Mutations on the Spike (S) …
spread more rapid than the other variants of SARS-CoV-2 virus. Mutations on the Spike (S) …
V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding …
J Ou, Z Zhou, R Dai, J Zhang, S Zhao, X Wu… - Journal of …, 2021 - Am Soc Microbiol
The current pandemic of COVID-19 is caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
[HTML][HTML] Improved binding affinity of omicron's spike protein for the human angiotensin-converting enzyme 2 receptor is the key behind its increased virulence
The new variant of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2),
Omicron, has been quickly spreading in many countries worldwide. Compared to the …
Omicron, has been quickly spreading in many countries worldwide. Compared to the …
[HTML][HTML] Reversal of the unique Q493R mutation increases the affinity of Omicron S1-RBD for ACE2
Abstract The SARS-CoV-2 Omicron variant containing 15 mutations, including the unique
Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While …
Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While …
Scanning the RBD-ACE2 molecular interactions in Omicron variant
The emergence of new SARS-CoV-2 variants poses a threat to the human population where
it is difficult to assess the severity of a particular variant of the virus. Spike protein and …
it is difficult to assess the severity of a particular variant of the virus. Spike protein and …
Omicron and Delta variant of SARS‐CoV‐2: a comparative computational study of spike protein
S Kumar, TS Thambiraja, K Karuppanan… - Journal of medical …, 2022 - Wiley Online Library
Emerging severe acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2) variants,
especially those of concern, may have an impact on the virus's transmissibility and …
especially those of concern, may have an impact on the virus's transmissibility and …
Binding interactions between receptor-binding domain of spike protein and human angiotensin converting enzyme-2 in omicron variant
B Jawad, P Adhikari, R Podgornik… - The journal of physical …, 2022 - ACS Publications
The emergence of new SARS-CoV-2 Omicron variant of concern (OV) has exacerbated the
COVID-19 pandemic because of a large number of mutations in the spike protein …
COVID-19 pandemic because of a large number of mutations in the spike protein …
[HTML][HTML] Insilico study on the effect of SARS-CoV-2 RBD hotspot mutants' interaction with ACE2 to understand the binding affinity and stability
J Verma, N Subbarao - Virology, 2021 - Elsevier
The fall of 2020 brought several new variants of SARS-CoV-2 circulating across the globe,
and the steadily increasing COVID-19 cases are responsible for the emergence of these …
and the steadily increasing COVID-19 cases are responsible for the emergence of these …
Distant residues modulate conformational opening in SARS-CoV-2 spike protein
D Ray, L Le, I Andricioaei - Proceedings of the National …, 2021 - National Acad Sciences
Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) involves the
attachment of the receptor-binding domain (RBD) of its spike proteins to the ACE2 receptors …
attachment of the receptor-binding domain (RBD) of its spike proteins to the ACE2 receptors …
Enhanced binding of the N501Y‐mutated SARS‐CoV‐2 spike protein to the human ACE2 receptor: insights from molecular dynamics simulations
Recently, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants (B. 1.1.
7 and B. 1351) have emerged harbouring mutations that make them highly contagious. The …
7 and B. 1351) have emerged harbouring mutations that make them highly contagious. The …
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