The nasal absorption of a range of water-soluble compounds with different molecular
weights, 4-oxo-4 H-1-benzopyran-2-carboxylic acid (mol. wt 190), p-aminohippuric acid …

Absorption of drugs through the nasal mucosa was studied to find out the suitability of the
nasal mucosa as a new site of administration. The in situ recirculation test with the nasal …

A series of polyethylene glycols (PEGs) ranging in molecular weight from near 600 to over
2000 daltons was used to study the effects of three absorption enhancers (sodium …

The effect of absorption promoters on the nasal absorption of drugs with different average
molecular weights was examined in rats. Phenol red and fluorescein isothiocyanate …

The effect of rate of perfusion, volume, pH of the perfusate, and partition coefficient of the
drug on the rate of in situ nasal absorption in rats was examined. The studies showed that …

An octapeptide and a protein, of molecular weights 800 and 34 000, respectively, were
found to have nasal bioavailabilities of 73 and 0.6%, respectively, in the rat. This data …

The objectives in the present study were to establish a useful in vitro experimental method
for detailed understanding of the nasal absorption of several drugs and its enhancement …

A series of fractionated di-iodo-l-tyrosine-labelled dextrans (DIT dextrans), with a narrow
range of number average molecular weights from 1260 to 45 500 Da, was administered …

Intranasal absorption has been demonstrated for various drugs, including peptidic
compounds, under a wide range of delivery conditions. However, little is known of the …

A method is described which enables the controlled assessment of the effects of intranasal
drug formulations on rat nasal epithelium. Damage to the nasal mucosa caused by the …