[HTML][HTML] A systematic review of immune checkpoint inhibitor–associated glomerular disease

A Kitchlu, KD Jhaveri, S Wadhwani… - Kidney international …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are increasingly used to treat cancers.
Kidney immune-related adverse events (IRAEs) are now well recognized, with the incidence …

[HTML][HTML] Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience

O Mamlouk, U Selamet, S Machado… - … for immunotherapy of …, 2019 - Springer
Abstract Rationale & Objective The approved therapeutic indication for immune checkpoint
inhibitors (CPIs) are rapidly expanding including treatment in the adjuvant setting, the …

Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury

B Sprangers, DE Leaf, C Porta, MJ Soler… - Nature Reviews …, 2022 - nature.com
Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors
(ICIs) have had an overwhelming impact on cancer treatment. Use of these agents in …

[HTML][HTML] Biomarkers, clinical features, and rechallenge for immune checkpoint inhibitor renal immune-related adverse events

B Isik, MP Alexander, S Manohar, L Vaughan… - Kidney International …, 2021 - Elsevier
Introduction Immune checkpoint inhibitors (ICIs) are effective in treating several cancers;
however, acute kidney injury (AKI) can occur as part as an immune-related adverse event …

Acute interstitial nephritis and checkpoint inhibitor therapy: single center experience of management and drug rechallenge

S Manohar, R Ghamrawi, M Chengappa, BNB Goksu… - Kidney360, 2020 - journals.lww.com
Background The objective of this case cohort study was to describe our experience in the
care of patients with immune checkpoint inhibitor–related acute interstitial nephritis (ICI-AIN) …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …

[HTML][HTML] Acute kidney injury associated with immune checkpoint inhibitor therapy: incidence, risk factors and outcomes

A Meraz-Muñoz, E Amir, P Ng… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICPi) are a novel and promising anti-cancer
therapy. There are limited data on the incidence, risk factors and outcomes of acute kidney …

Immune checkpoint inhibitor nephrotoxicity: update 2020

S Gupta, FB Cortazar, LV Riella, DE Leaf - Kidney360, 2020 - journals.lww.com
Immune checkpoint inhibitors (ICPIs) have transformed the landscape of oncology, but are
associated with a variety of autoimmune adverse events, including AKI. ICPI-associated AKI …

Diagnosis and management of immune checkpoint inhibitor‐associated renal toxicity: illustrative case and review

ME Sise, H Seethapathy, KL Reynolds - The Oncologist, 2019 - academic.oup.com
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies directed at negative
regulatory components on T cells, such as cytotoxic T lymphocyte‐associated antigen 4 …

[HTML][HTML] Renal adverse effects of immune checkpoints inhibitors in clinical practice: ImmuNoTox study

M Espi, C Teuma, E Novel-Catin, D Maillet… - European Journal of …, 2021 - Elsevier
Abstract Background/objectives Acute Kidney Injury (AKI), induced by Checkpoint Inhibitors
therapies (CPI-induced AKI), is an uncommon but severe Immune-Related Adverse Event …