Current developments in tissue engineering and microtechnology fields have allowed the
proposal of pertinent tools, microchips, to investigate in vitro toxicity. In the framework of the …

The adoption of a new technology into basic research, and industrial and clinical settings
requires rigorous testing to build confidence in the reproducibility, reliability, robustness, and …

Pharmaceutical drug screening and research into diseases call for significant improvement
in the effectiveness of current in vitro models. Better models would reduce the likelihood of …

Abstract Development of a bioartificial renal tubule with a confluent monolayer of renal
epithelial cells supported on a permeable synthetic surface may be the first step to further …

The use of a bioartificial renal tubule device composed of renal proximal tubule cells grown
within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide …

Current developments in the technological fields of liver tissue engineering, bioengineering,
biomechanics, microfabrication and microfluidics have lead to highly complex and pertinent …

Tubulogenesis in epithelial organs often initiates with the acquisition of apicobasal polarity,
giving rise to the formation of small lumens that expand and fuse to generate a single …

Tissue engineering of a bioartificial renal tubule assist device: In vitro transport and
metabolic characteristics. Background Current renal substitution therapy for acute or chronic …

The renal proximal tubule epithelium is responsible for active secretion of endogenous and
exogenous waste products from the body and simultaneous reabsorption of vital compounds …

The ability to culture cells in vitro has revolutionized hypothesis testing in basic cell and
molecular biology research and has become a standard methodology in drug screening and …