Background Hepatic perfusion plays a crucial role in liver transplantation strategies, for
example, when preserving procured organs with the use of machine perfusion preservation …

Due to the growing shortage of donor livers, more patients are waiting for transplantation.
Living donor liver transplantation may help expanding the donor pool, but is often confronted …

The perfusion of the liver microcirculation is often analyzed in terms of idealized functional
units (hexagonal liver lobules) based on a porous medium approach. More elaborate …

Liver structures of a healthy subject are digitised and segmented from computed
tomography (CT) images, and hepatic perfusion is modelled in the hepatic artery and portal …

Availability of donor livers and the relatively short preservation time limit the success of liver
transplantation. The use of hypothermic machine perfusion could pave the way for …

Background and objective Blood flow rate and pressure can be measured in vivo by
invasive and non-invasive techniques in the large vessels of the hepatic vasculature, but it is …

Blood flow in the liver has several unique features compared with other organs in the body.
The liver is made up of functional units called lobules, and blood flows across the lobules …

The liver plays a key role in the metabolic homeostasis of the whole organism. To carry out
its functions, it is endowed with a peculiar circulatory system, made of three main dendritic …

Objectives: Hypothermic machine perfusion (HMP) of livers is being developed as a
potentially better preservation method than cold storage. The challenge is to define the …

This study used magnetic resonance imaging (MRI), computational fluid dynamics (CFD)
modelling and in vitro experiments to predict patient-specific alterations in hepatic …