[HTML][HTML] Helicobacter pylori infection synergistic with IL-1β gene polymorphisms potentially contributes to the carcinogenesis of gastric cancer

JB Hong, W Zuo, AJ Wang, NH Lu - International journal of medical …, 2016 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in the
world and the etiological agent for most gastric cancer (GC). Interleukin-1β (IL-1β) is a potent …

Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population

S Kumar, A Kumar, VK Dixit - Biochemical and biophysical research …, 2009 - Elsevier
Helicobacter pylori infection is strongly associated with gastric cancer. In the present study,
the relationship between interleukin-1B (IL-1B) polymorphism, H. pylori infection, and …

Association between interleukin‐1 gene polymorphisms and Helicobacter pylori infection in gastric carcinogenesis in a Chinese population

C Li, HHX Xia, W Xie, Z Hu, M Ye, J Li… - Journal of …, 2007 - Wiley Online Library
Abstract Background and Aim: Helicobacter pylori is a major cause of chronic gastritis and
peptic ulcer disease and a definite carcinogen for gastric adenocarcinoma. However, the …

Association of genetic polymorphisms of interleukins with gastric cancer and precancerous gastric lesions in a high-risk Chinese population

YM Wang, ZX Li, FB Tang, Y Zhang, T Zhou, L Zhang… - Tumor Biology, 2016 - Springer
Helicobacter pylori (H. pylori) infection and cytokine-mediated inflammatory responses play
important roles in gastric cancer (GC) pathogenesis. To investigate an association between …

Interleukin‐1B 31 C>T polymorphism combined with Helicobacter pylori‐modified gastric cancer susceptibility: evidence from 37 studies

HY Ying, BW Yu, Z Yang, SS Yang… - Journal of cellular …, 2016 - Wiley Online Library
Gastric cancer is one of the most common malignancies worldwide. Interleukin‐1‐beta (IL‐
1β) is a pro‐inflammatory cytokine and potent inhibitor of gastric acid secretion. Some …

Combination of Interleukin 1 Polymorphism and Helicobacter pylori Infection: an Increased Risk of Gastric Cancer in Pakistani Population

Y Raza, A Khan, AI Khan, S Khan, S Akhter… - Pathology & Oncology …, 2017 - Springer
Helicobacter pylori is one of the major risk factors involved in the development ofgastritis
and gastric cancer (GC). H. pylori infection leads to increased production of pro …

Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor α and risk of gastric cancer in a Chinese population

W Lu, K Pan, L Zhang, D Lin, X Miao, W You - Carcinogenesis, 2005 - academic.oup.com
Helicobacter pylori infection and the cytokine-mediated inflammatory responses play
important roles in gastric cancer pathogenesis. This case control study was conducted to …

[HTML][HTML] Role of interleukin polymorphisms in gastric cancer:“Pros and cons”

F Perri, F Terracciano, M Gentile, A Merla… - World Journal of …, 2010 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is the leading cause of gastric cancer worldwide.
Infection with this bacterium causes a chronic active immune response that persists for the …

[HTML][HTML] Role of polymorphisms in genes that encode cytokines and Helicobacter pylori virulence factors in gastric carcinogenesis

BB de Brito, FAF da Silva… - World Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
The Helicobacter pylori (H. pylori) infection is a determinant factor in gastric cancer (GC)
development. However, the infection outcomes are variable and depend on both host and …

Polymorphisms and haplotypes of the interleukin 2 gene are associated with an increased risk of gastric cancer. The possible involvement of Helicobacter pylori

JL Melchiades, LM Zabaglia, ML Sallas, WA Orcini… - Cytokine, 2017 - Elsevier
Abstract Interleukin 2 (IL-2) is a pro-inflammatory cytokine that is mainly synthesized by
immunoregulatory T helper cells and which plays an important role in antitumor immunity …