Herein, we report a nongenetic and real-time approach for imaging protein dimerization on
living cell surfaces by aptamer recognition and proximity-induced DNA assembly. We use …

Protein dimerization or oligomerization is a key factor in signal transduction processes. It is
of great significance to develop novel strategies for investigating protein dimerization in cells …

On cell-membrane surfaces, receptor-protein dimers play fundamental roles in many
signaling pathways that are crucial for normal biological processes and cancer …

Cell surface receptors play a critical role in modulating intracellular signal transduction,
making them important drug targets. However, it remains challenging to develop a selective …

An important goal of nanotechnology is to assemble multiple molecules while controlling the
spacing between them. Of particular interest is the phenomenon of multivalency, which is …

Direct cellular imaging of the localization and dynamics of biomolecules helps to understand
their function and reveals novel mechanisms at the single‐cell resolution. In contrast to …

Dimerization of proteins occurs frequently and plays integral roles in biological processes.
However, no single molecular probe is available for in situ detection of protein dimers on …

The formation and dissociation of protein complexes plays an important role in numerous
biological processes. Small molecules can be used as tools to induce protein–protein …

In biology, membrane-spanning proteins are responsible for the transmission of chemical
signals across membranes, including the signal recognition-mediated conformational …

Cell surface proteins are an important class of biomarkers for fundamental biological
research and for disease diagnostics and treatment. In this communication, we report a …