Large-scale association analysis identifies new risk loci for coronary artery disease
CARDIoGRAMplusC4D Consortium, P Deloukas… - Nature …, 2013 - nature.com
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
H Schunkert, IR König, S Kathiresan, MP Reilly… - Nature …, 2011 - nature.com
We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …
Association analyses based on false discovery rate implicate new loci for coronary artery disease
Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …
A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
Nature genetics, 2015 - nature.com
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is
largely based on genome-wide association study (GWAS) analysis of common SNPs …
largely based on genome-wide association study (GWAS) analysis of common SNPs …
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
The majority of the heritability of coronary artery disease (CAD) remains unexplained,
despite recent successes of genome-wide association studies (GWAS) in identifying novel …
despite recent successes of genome-wide association studies (GWAS) in identifying novel …
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford… - Nature …, 2022 - nature.com
The discovery of genetic loci associated with complex diseases has outpaced the
elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide …
elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide …
Genomewide association analysis of coronary artery disease
Background Modern genotyping platforms permit a systematic search for inherited
components of complex diseases. We performed a joint analysis of two genomewide …
components of complex diseases. We performed a joint analysis of two genomewide …
Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour
JF Peden, M Farrall - Human molecular genetics, 2011 - academic.oup.com
Coronary artery disease (CAD) is the leading cause of death worldwide. Affected individuals
cluster in families in patterns that reflect the sharing of numerous susceptibility genes …
cluster in families in patterns that reflect the sharing of numerous susceptibility genes …
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
We report a genome-wide association study (GWAS) of coronary artery disease (CAD)
incorporating nearly a quarter of a million cases, in which existing studies are integrated with …
incorporating nearly a quarter of a million cases, in which existing studies are integrated with …
Large scale association analysis identifies three susceptibility loci for coronary artery disease
S Saade, JB Cazier, M Ghassibe-Sabbagh… - PloS one, 2011 - journals.plos.org
Genome wide association studies (GWAS) and their replications that have associated DNA
variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are …
variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are …
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