Baicalin promotes the activation of brown and white adipose tissue through AMPK/PGC1α pathway
Y Zhang, Z Zhang, Y Zhang, L Wu, L Gao, R Yao… - European Journal of …, 2022 - Elsevier
Obesity occurs when energy intake overtops energy expenditure. Promoting activation of
brown adipose tissue (BAT) and white adipose tissue (WAT) has been proven a promising …
brown adipose tissue (BAT) and white adipose tissue (WAT) has been proven a promising …
The mechanisms of baicalin ameliorate obesity and hyperlipidemia through a network pharmacology approach
ZY Wang, ZM Jiang, PT Xiao, YQ Jiang, WJ Liu… - European Journal of …, 2020 - Elsevier
Obesity is one of the main causes of human cardiovascular and cerebrovascular diseases.
Baicalin, a bioactive flavonoid isolated from the herbal medicine Scutellaria baicalensis …
Baicalin, a bioactive flavonoid isolated from the herbal medicine Scutellaria baicalensis …
Baicalin against obesity and insulin resistance through activation of AKT/AS160/GLUT4 pathway
P Fang, M Yu, L Zhang, D Wan, M Shi, Y Zhu… - Molecular and cellular …, 2017 - Elsevier
Obesity may cause several metabolic complications, including insulin resistance and type 2
diabetes mellitus. Despite great advances in medicine, people still keep exploring novel and …
diabetes mellitus. Despite great advances in medicine, people still keep exploring novel and …
Baicalin attenuates diet-induced obesity partially through promoting thermogenesis in adipose tissue
H Li, S Tang - Obesity research & clinical practice, 2021 - Elsevier
Background Adipose tissues have essential roles on energy homeostasis and the
development of metabolic syndrome and obesity, they have become critical targets for …
development of metabolic syndrome and obesity, they have become critical targets for …
Baicalin attenuates high fat diet-induced insulin resistance and ectopic fat storage in skeletal muscle, through modulating the protein kinase B/Glycogen synthase …
XI You-Li, LI Hong-Xia, C Chen, LIU Ya-Qun… - Chinese Journal of …, 2016 - Elsevier
Insulin resistance is the pathophysiological basis of many diseases. Overcoming early
insulin resistance highly significant in prevention diabetes, non-alcoholic fatty liver, and …
insulin resistance highly significant in prevention diabetes, non-alcoholic fatty liver, and …
Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway
In this study, the antiobesity effects of baicalin, 5, 6‐dihydroxyflavone‐7‐glucuronic acid,
were characterized using an in vitro system of adipogenesis, ie fat cell formation. Baicalin …
were characterized using an in vitro system of adipogenesis, ie fat cell formation. Baicalin …
Baicalin and its aglycone: a novel approach for treatment of metabolic disorders
P Fang, M Yu, M Shi, P Bo, X Gu, Z Zhang - Pharmacological Reports, 2020 - Springer
Background The current strategies for prevention and treatment of insulin resistance and
type 2 diabetes are not fully effective and frequently accompanied by many negative effects …
type 2 diabetes are not fully effective and frequently accompanied by many negative effects …
Baicalin and its metabolites suppresses gluconeogenesis through activation of AMPK or AKT in insulin resistant HepG-2 cells
T Wang, H Jiang, S Cao, Q Chen, M Cui, Z Wang… - European Journal of …, 2017 - Elsevier
Scutellaria baicalensis Georgi (S. baicalensis), as a traditional Chinese herbal medicine, is
an important component of several famous Chinese medicinal formulas for treating patients …
an important component of several famous Chinese medicinal formulas for treating patients …
[HTML][HTML] Baicalin attenuates high fat diet-induced obesity and liver dysfunction: dose-response and potential role of CaMKKβ/AMPK/ACC pathway
Y Xi, M Wu, H Li, S Dong, E Luo, M Gu… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Obesity-associated fatty liver disease affects millions of individuals. This
study aimed to evaluate the therapeutic effects of baicalin to treat obesity and fatty liver in …
study aimed to evaluate the therapeutic effects of baicalin to treat obesity and fatty liver in …
Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling
M Yu, S Han, M Wang, L Han, Y Huang, P Bo, P Fang… - Phytomedicine, 2022 - Elsevier
Background Type 2 diabetes mellitus is a complex metabolic disorder associated with
obesity, glucose intolerance and insulin resistance. Activation of GALR2 has been proposed …
obesity, glucose intolerance and insulin resistance. Activation of GALR2 has been proposed …