Improvement of the folliculogenesis by transplantation of bone marrow mesenchymal stromal cells in mice with induced polycystic ovary syndrome

Z Kalhori, M Azadbakht, MS Mehranjani… - Cytotherapy, 2018 - Elsevier
Background Many studies have reported that inflammation and oxidative stress are involved
in the pathogenesis of polycystic ovary syndrome (PCOS). Bone marrow mesenchymal …

Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10

RM Chugh, H Park, A El Andaloussi… - Stem Cell Research & …, 2021 - Springer
Background Polycystic ovary syndrome (PCOS) is the most common endocrine and
metabolic disorder in reproductive-age women. Excessive inflammation and elevated …

Effects of VEGF + Mesenchymal Stem Cells and Platelet-Rich Plasma on Inbred Rat Ovarian Functions in Cyclophosphamide …

B Vural, G Duruksu, F Vural, M Gorguc… - Stem cell reviews and …, 2019 - Springer
Premature ovarian insufficiency (POI), a fertility disorder affecting women under 40 years of
age, is characterized by early loss of ovarian function. This study was aimed to maintain …

Mechanistic action of mesenchymal stem cell injection in the treatment of chemically induced ovarian failure in rabbits

SH Abd-Allah, SM Shalaby, HF Pasha, S Amal… - Cytotherapy, 2013 - Elsevier
Background No curative treatment is known for primary ovarian failure; however,
mesenchymal stem cells (MSCs), through self-renewal and regeneration, push the trial to …

[HTML][HTML] Effect of transplantation of bone marrow stromal cell-conditioned medium on ovarian function, morphology and cell death in cyclophosphamide-treated rats

N Khanmohammadi, HR Sameni… - Cell Journal …, 2018 - ncbi.nlm.nih.gov
Objective Although stem cell transplantation has beneficial effects on tissue regeneration,
but there are still problems such as high cost and safety issues. Since stem cell therapy is …

Role of mesenchymal stem cell therapy in restoring ovarian function in a rat model of chemotherapy-induced ovarian failure: a histological and immunohistochemical …

NM Afifi, ON Reyad - Egyptian Journal of Histology, 2013 - journals.lww.com
Aim of the work The present study was carried out to examine the role of mesenchymal stem
cell (MSC) transplantation on ovarian function using a rat model of chemotherapy-induced …

[HTML][HTML] Human embryonic stem cell-derived mesenchymal stem cells improved premature ovarian failure

K Bahrehbar, MR Valojerdi, F Esfandiari… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Premature ovarian failure (POF) affects many adult women less than 40
years of age and leads to infertility. According to previous reports, various tissue-specific …

Mesenchymal stem cells alleviate DHEA‐induced polycystic ovary syndrome (PCOS) by inhibiting inflammation in mice

Q Xie, XL Xiong, N Xiao, K He, M Chen… - Stem cells …, 2019 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in
women of reproductive age. Chronic inflammation is considered to be the cause of ovarian …

Potential of mesenchymal stem cells and their secretomes in decreasing inflammation markers in polycystic ovary syndrome treatment: A systematic review

GD Prayitno, K Lestari, CR Sartika, T Djuwantono… - Medicines, 2022 - mdpi.com
Background: Polycystic ovary syndrome (PCOS) is a chronic disorder and is one of the most
common endocrine disorders in women of a reproductive age. The prevalence of PCOS is …

[HTML][HTML] Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway

J Cho, TH Kim, J Seok, JH Jun, H Park, M Kweon… - Laboratory …, 2021 - Elsevier
Angiogenesis plays an important role in damaged organ or tissue and cell regeneration and
ovarian development and function. Primary ovarian insufficiency (POI) is a prevalent …