Objective To observe the analgesic effect of early hyperbaric oxygen (HBO) treatment in
chronic constriction injury (CCI) rats, and to analyze the influence of HBO on the expression …

BACKGROUND: Neuropathic pain is complex, and a satisfactory therapeutic method of
treatment has yet to be developed; therefore, finding a new and effective therapeutic method …

Neuropathic pain is pain caused by injury or dysfunction in the central and/or peripheral
nervous system. Neuropathic pain has a high incidence with a complex mechanism, but …

BACKGROUND: The development of hyperalgesia and allodynia after chronic constrictive
injury (CCI) is associated with significantly increased tumor necrosis factor (TNF)-α and …

Background Hyperbaric oxygen (HBO) has the potential to relieve neuropathic pain. The
purpose of this study was to determine whether the NO-cGMP-PKG signaling pathway is …

Hyperbaric oxygen treatment (HBOT) has been used to reduce neuropathic pain. Melatonin
and opioid receptors are involved in neuropathic pain, but it is not known if HBOT works …

Abstract Hyperbaric oxygen (HBO) treatment has been proven to be a promising candidate
for protection of the nervous system after acute injury in animal models of neuropathic pain …

Earlier research has demonstrated that hyperbaric oxygen (HBO 2) can produce an
antinociceptive effect in models of acute pain. Recent studies have revealed that HBO 2 can …

Hyperbaric oxygen (HBO) treatment has been used clinically to treat a variety of ailments,
including severe burns and carbon monoxide poisoning, and in research settings has …

Research has demonstrated that hyperbaric oxygen (HBO 2) treatment produced relief of
both acute and chronic pain in patients and animal models. However, the mechanism of …