Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1)
macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by …

A growing number of findings highlight the crucial role of metabolic reprogramming in
macrophage activation. Metabolic pathways are closely interconnected and recent literature …

Macrophages are not only essential components of innate immunity that contribute to host
defense against infections, but also tumor growth and the maintenance of tissue …

Metabolic adaptation is a key component of macrophage plasticity and polarization,
instrumental to their function in homeostasis, immunity, and inflammation. Macrophage …

Metabolic reprogramming has emerged as a crucial regulator of immune cell activation, but
how systemic metabolism influences immune cell metabolism and function remains to be …

Traditionally cellular respiration or metabolism has been viewed as catabolic and anabolic
pathways generating energy and biosynthetic precursors required for growth and general …

Macrophages and lymphocytes demonstrate metabolic plasticity, which is dependent partly
on their state of activation and partly on the availability of various energy yielding and …

Distinct macrophage populations throughout the body display highly heterogeneous
transcriptional and epigenetic programs. Recent research has highlighted that these profiles …

Macrophages are innate immune cells that provide host defense and have tissue-specific
roles in the maintenance of organ homeostasis and integrity. In most cases macrophages …

Macrophages are cells of the innate immune system that regulate the maintenance of tissue
homeostasis, host defense during pathogen infection, and tissue repair in response to tissue …