Background Cancer is widely regarded as a complex disease primarily driven by genetic
mutations. A critical concern and significant obstacle lies in discerning driver genes amid an …

Although numerous approaches have been proposed to discern driver from passenger,
identification of driver genes remains a critical challenge in the cancer genomics field. Driver …

Driver genes play a crucial role in the growth of cancer cells. Accurate identification of
cancer driver genes is helping to strengthen the understanding of cancer pathogenesis and …

Identifying personalized driver genes is essential for discovering critical biomarkers and
developing effective personalized therapies of cancers. However, few methods consider …

Cancer is known as a disease mainly caused by gene alterations. Discovery of mutated
driver pathways or gene sets is becoming an important step to understand molecular …

Cancer is a genomic disease associated with a plethora of gene mutations resulting in a
loss of control over vital cellular functions. Among these mutated genes, driver genes are …

Background Recent advances in next-generation sequencing technologies have helped
investigators generate massive amounts of cancer genomic data. A critical challenge in …

Integration of multi‐omics data of cancer can help people to explore cancers
comprehensively. However, with a large volume of different omics and functional data being …

Comprehensive analysis of multiple data sets can identify potential driver genes for various
cancers. In recent years, driver gene discovery based on massive mutation data and gene …

Identifying driver modules or pathways is a key challenge to interpret the molecular
mechanisms and pathogenesis underlying cancer. An increasing number of studies suggest …