DriverMP enables improved identification of cancer driver genes
Y Liu, J Han, T Kong, N Xiao, Q Mei, J Liu - GigaScience, 2023 - academic.oup.com
Background Cancer is widely regarded as a complex disease primarily driven by genetic
mutations. A critical concern and significant obstacle lies in discerning driver genes amid an …
mutations. A critical concern and significant obstacle lies in discerning driver genes amid an …
[HTML][HTML] Integrating omics data and protein interaction networks to prioritize driver genes in cancer
T Zhang, D Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Although numerous approaches have been proposed to discern driver from passenger,
identification of driver genes remains a critical challenge in the cancer genomics field. Driver …
identification of driver genes remains a critical challenge in the cancer genomics field. Driver …
Trans-Driver: a deep learning approach for cancer driver gene discovery with multi-omics data
Driver genes play a crucial role in the growth of cancer cells. Accurate identification of
cancer driver genes is helping to strengthen the understanding of cancer pathogenesis and …
cancer driver genes is helping to strengthen the understanding of cancer pathogenesis and …
An efficient and easy-to-use network-based integrative method of multi-omics data for cancer genes discovery
T Wei, B Fa, C Luo, L Johnston, Y Zhang, Z Yu - Frontiers in genetics, 2021 - frontiersin.org
Identifying personalized driver genes is essential for discovering critical biomarkers and
developing effective personalized therapies of cancers. However, few methods consider …
developing effective personalized therapies of cancers. However, few methods consider …
Discovery of cancer common and specific driver gene sets
J Zhang, S Zhang - Nucleic acids research, 2017 - academic.oup.com
Cancer is known as a disease mainly caused by gene alterations. Discovery of mutated
driver pathways or gene sets is becoming an important step to understand molecular …
driver pathways or gene sets is becoming an important step to understand molecular …
Identifying potential cancer driver genes by genomic data integration
Cancer is a genomic disease associated with a plethora of gene mutations resulting in a
loss of control over vital cellular functions. Among these mutated genes, driver genes are …
loss of control over vital cellular functions. Among these mutated genes, driver genes are …
DriverRWH: discovering cancer driver genes by random walk on a gene mutation hypergraph
C Wang, J Shi, J Cai, Y Zhang, X Zheng, N Zhang - BMC bioinformatics, 2022 - Springer
Background Recent advances in next-generation sequencing technologies have helped
investigators generate massive amounts of cancer genomic data. A critical challenge in …
investigators generate massive amounts of cancer genomic data. A critical challenge in …
DriverFinder: A Gene Length‐Based Network Method to Identify Cancer Driver Genes
PJ Wei, D Zhang, HT Li, J Xia, CH Zheng - Complexity, 2017 - Wiley Online Library
Integration of multi‐omics data of cancer can help people to explore cancers
comprehensively. However, with a large volume of different omics and functional data being …
comprehensively. However, with a large volume of different omics and functional data being …
Network embedding framework for driver gene discovery by combining functional and structural information
X Chu, B Guan, L Dai, J Liu, F Li, J Shang - BMC genomics, 2023 - Springer
Comprehensive analysis of multiple data sets can identify potential driver genes for various
cancers. In recent years, driver gene discovery based on massive mutation data and gene …
cancers. In recent years, driver gene discovery based on massive mutation data and gene …
Detection of driver modules with rarely mutated genes in cancers
F Li, L Gao, B Wang - IEEE/ACM Transactions on …, 2018 - ieeexplore.ieee.org
Identifying driver modules or pathways is a key challenge to interpret the molecular
mechanisms and pathogenesis underlying cancer. An increasing number of studies suggest …
mechanisms and pathogenesis underlying cancer. An increasing number of studies suggest …