A complete understanding of the interactions between nanoparticles (NPs) and the cell
membrane is essential for the potential biomedical applications of NPs. The rotation of the …

We present a thermodynamic approach to elucidate the effects of the size and shape of
nanoparticles (NPs) on endocytosis. It is found that endocytosis needs to surmount a …

Nanoparticles (NPs) have been widely applied as drug carriers in drug delivery, due to their
unique physical and structural properties. To achieve the drug delivery purpose, receptor …

Using coarse-grained molecular dynamics simulations, we systematically investigate the
receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging …

It is increasingly recognized that the investigation of the rotational motion of geometric
nanoparticles in the cellular internalization process is significant to understand certain …

Nanoparticles (NPs) hold great promises for targeted disease diagnosis and therapy.
Despite considerable progress in biomimetic design of NP-bioconjugates, the roles of NP …

A fundamental understanding of the interactions between nanoparticles (NPs) and the cell
membrane is essential to improve the performance of the NP-based biomedical applications …

Understanding the endocytic process of nanoparticles (NPs) with different mechanical
rigidities is critical to develop effective drug delivery vectors. Here, we perform experiments …

Cellular uptake through endocytosis is crucial for drug delivery and nanomedicine.
However, the conditions under which passive endocytosis (ie, not ATP driven) takes place …

The uptake of nanoparticles (NPs) by a cellular membrane is known to be NP size
dependent, but the pathway and kinetics for the endocytosis of multiple NPs still remain …