Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

JF Garvey, CT Taylor… - European Respiratory …, 2009 - Eur Respiratory Soc
There is increasing evidence that intermittent hypoxia plays a role in the development of
cardiovascular risk in obstructive sleep apnoea syndrome (OSAS) through the activation of …

Intermittent hypoxia and activation of inflammatory molecular pathways in OSAS

S Ryan, WT McNicholas - Archives of physiology and biochemistry, 2008 - Taylor & Francis
Obstructive sleep apnoea syndrome (OSAS) represents a highly prevalent disease and is
recognized as a risk factor for the development of various cardiovascular disorders. The …

Obstructive sleep apnea and inflammation: relationship to cardiovascular co-morbidity

BD Kent, S Ryan, WT McNicholas - Respiratory physiology & neurobiology, 2011 - Elsevier
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and associated
with cardiovascular morbidity and mortality. The pathogenesis of cardiovascular …

Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?

S Ryan, CT Taylor… - Postgraduate medical …, 2009 - academic.oup.com
Obstructive sleep apnoea syndrome (OSAS) is a highly prevalent disease and is recognised
as a major public health burden. Large-scale epidemiological studies have demonstrated an …

[HTML][HTML] Mechanisms of cardiovascular disease in obstructive sleep apnoea

S Ryan - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
Obstructive sleep apnoea (OSA) is recognized as a major public health burden conveying a
significant risk of cardiovascular diseases (CVD) and mortality. Continuous positive airway …

Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome

S Ryan, CT Taylor, WT McNicholas - Circulation, 2005 - Am Heart Assoc
Background—Obstructive sleep apnea syndrome (OSAS), characterized by intermittent
hypoxia/reoxygenation (IHR), is an independent risk factor for cardiovascular disease. We …

Cardiovascular aspects in obstructive sleep apnea syndrome–molecular issues, hypoxia and cytokine profiles

L Lavie, V Polotsky - Respiration, 2009 - karger.com
Obstructive sleep apnea syndrome (OSAS), which is a highly prevalent breathing disorder in
sleep, is an independent risk factor for cardiovascular morbidity and mortality. Results from …

Obstructive sleep apnea and inflammation

WT McNicholas - Progress in cardiovascular diseases, 2009 - Elsevier
The pathogenesis of cardiovascular complications in obstructive sleep apnea syndrome
(OSAS) is not fully understood but is likely multifactorial in origin. Inflammatory processes …

Obstructive sleep apnoea and cardiovascular consequences: pathophysiological mechanisms

C Arnaud, T Bochaton, JL Pépin, E Belaidi - Archives of cardiovascular …, 2020 - Elsevier
Obstructive sleep apnoea syndrome is a growing health concern, affecting nearly one billion
people worldwide; it is an independent cardiovascular risk factor, associated with incident …

Obstructive sleep apnea: role of intermittent hypoxia and inflammation

AM May, R Mehra - Seminars in respiratory and critical care …, 2014 - thieme-connect.com
Obstructive sleep apnea results in intermittent hypoxia via repetitive upper airway
obstruction leading to partial or complete upper airway closure, apneas and hypopneas …