Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study
Background & Aims Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibrotic
liver disease that can lead to cirrhosis. While liver biopsy is considered the reference …
liver disease that can lead to cirrhosis. While liver biopsy is considered the reference …
Relationship between three commonly used non‐invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non‐alcoholic steatohepatitis
Abstract Background & Aims Non‐invasive biomarkers are needed for monitoring changes
in liver histology in patients with non‐alcoholic steatohepatitis (NASH). Obeticholic acid …
in liver histology in patients with non‐alcoholic steatohepatitis (NASH). Obeticholic acid …
[PDF][PDF] qFIBS: an automated technique for quantitative evaluation of fibrosis, inflammation, ballooning, and steatosis in patients with nonalcoholic steatohepatitis
F Liu, GBB Goh, D Tiniakos, A Wee, WQ Leow… - …, 2020 - Wiley Online Library
Background and Aims Nonalcoholic steatohepatitis (NASH) is a common cause of chronic
liver disease. Clinical trials use the NASH Clinical Research Network (CRN) system for …
liver disease. Clinical trials use the NASH Clinical Research Network (CRN) system for …
Noninvasive tests accurately identify advanced fibrosis due to NASH: baseline data from the STELLAR trials
Accurate noninvasive tests (NITs) are needed to replace liver biopsy for identifying
advanced fibrosis caused by nonalcoholic steatohepatitis (NASH). We analyzed screening …
advanced fibrosis caused by nonalcoholic steatohepatitis (NASH). We analyzed screening …
The association of histologic and noninvasive tests with adverse clinical and patient-reported outcomes in patients with advanced fibrosis due to nonalcoholic …
Background & Aim Fibrosis is an independent predictor of death in nonalcoholic
steatohepatitis (NASH). We assessed the associations between histologic and noninvasive …
steatohepatitis (NASH). We assessed the associations between histologic and noninvasive …
Current complications and challenges in nonalcoholic steatohepatitis screening and diagnosis
Nonalcoholic steatohepatitis (NASH) can lead to complications such as liver failure, cirrhosis
and hepatocellular carcinoma. The diagnostic gold standard for NASH is liver biopsy; …
and hepatocellular carcinoma. The diagnostic gold standard for NASH is liver biopsy; …
MRI-based (MAST) score accurately identifies patients with NASH and significant fibrosis
M Noureddin, E Truong, JA Gornbein, R Saouaf… - Journal of …, 2022 - Elsevier
Background & Aims Among the large population of patients with non-alcoholic fatty liver
disease (NAFLD), identifying those with fibrotic non-alcoholic steatohepatitis (Fibro-NASH) …
disease (NAFLD), identifying those with fibrotic non-alcoholic steatohepatitis (Fibro-NASH) …
[HTML][HTML] Liver fibrosis markers of nonalcoholic steatohepatitis
H Enomoto, Y Bando, H Nakamura… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of chronic liver injury.
NAFLD includes a wide range of clinical conditions from simple steatosis to nonalcoholic …
NAFLD includes a wide range of clinical conditions from simple steatosis to nonalcoholic …
[PDF][PDF] Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future
A Wieckowska, AJ McCullough, AE Feldstein - Hepatology, 2007 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
United States, and its prevalence is increasing worldwide. It currently affects approximately …
United States, and its prevalence is increasing worldwide. It currently affects approximately …
[PDF][PDF] Improvements in histologic features and diagnosis associated with improvement in fibrosis in nonalcoholic steatohepatitis: results from the nonalcoholic …
EM Brunt, DE Kleiner, LA Wilson, AJ Sanyal… - …, 2019 - Wiley Online Library
Hepatocellular injury and inflammation are believed to be the primary drivers of fibrogenesis
that ultimately lead to cirrhosis in patients with nonalcoholic steatohepatitis (NASH). This …
that ultimately lead to cirrhosis in patients with nonalcoholic steatohepatitis (NASH). This …