Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations
JA Martinez-Climent, AA Alizadeh… - Blood, The Journal …, 2003 - ashpublications.org
Genomic aberrations in a series of paired biopsy samples from patients who presented
initially with follicle center lymphoma (FCL) and subsequently transformed to diffuse large B …
initially with follicle center lymphoma (FCL) and subsequently transformed to diffuse large B …
Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma
A Bouska, TW McKeithan… - Blood, The Journal …, 2014 - ashpublications.org
Follicular lymphoma (FL), the second most common type of non-Hodgkin lymphoma in the
western world, is characterized by the t (14; 18) translocation, which is present in up to 90 …
western world, is characterized by the t (14; 18) translocation, which is present in up to 90 …
[HTML][HTML] Gene expression profile of serial samples of transformed B-cell lymphomas
S de Vos, WK Hofmann, TM Grogan, U Krug… - Laboratory …, 2003 - Elsevier
Follicular lymphoma (FL) is characterized by a continuous rate of relapse and transformation
to a high-grade lymphoma, usually diffuse large B-cell lymphoma (DLBCL), associated with …
to a high-grade lymphoma, usually diffuse large B-cell lymphoma (DLBCL), associated with …
Copy number gain at 12q12-14 may be important in the transformation from follicular lymphoma to diffuse large B cell lymphoma
RE Hough, JR Goepel, HE Alcock, BW Hancock… - British journal of …, 2001 - nature.com
The purpose of this study was to identify novel areas of genomic copy number change
associated with transformation from follicular lymphoma (FL) to diffuse large B cell …
associated with transformation from follicular lymphoma (FL) to diffuse large B cell …
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
MB Eide, K Liestøl, OC Lingjærde… - Blood, The Journal …, 2010 - ashpublications.org
Our aim was to examine the genetics of clonal evolution in follicular lymphoma (FL) and to
identify genetic alterations associated with disease progression. A total of 100 biopsies from …
identify genetic alterations associated with disease progression. A total of 100 biopsies from …
Genetics of follicular lymphoma transformation
L Pasqualucci, H Khiabanian, M Fangazio… - Cell reports, 2014 - cell.com
Follicular lymphoma (FL) is an indolent disease, but 30%–40% of cases undergo histologic
transformation to an aggressive malignancy, typically represented by diffuse large B cell …
transformation to an aggressive malignancy, typically represented by diffuse large B cell …
Follicular lymphomas with and without translocation t (14; 18) differ in gene expression profiles and genetic alterations
E Leich, I Salaverria, S Bea, A Zettl… - Blood, The Journal …, 2009 - ashpublications.org
Follicular lymphoma (FL) is genetically characterized by the presence of the t (14; 18)(q32;
q21) chromosomal translocation in approximately 90% of cases. In contrast to FL carrying …
q21) chromosomal translocation in approximately 90% of cases. In contrast to FL carrying …
Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated Bcl-2 gene
A Matolcsy, P Casali, RA Warnke, DM Knowles - 1996 - ashpublications.org
Follicular lymphoma (FL) is a low-grade B-cell non-Hodgkin's lymphoma (NHL) that
frequently transforms into diffuse aggressive NHL. The majority of FLs display at (14; 18) …
frequently transforms into diffuse aggressive NHL. The majority of FLs display at (14; 18) …
Variable heavy chain gene analysis of follicular lymphomas: correlation between heavy chain isotype expression and somatic mutation load
WM Aarts, RJ Bende, EJ Steenbergen… - Blood, The Journal …, 2000 - ashpublications.org
The expansion of follicular lymphomas (FLs) resembles, both morphologically and
functionally, normal germinal center B-cell growth. The tumor cells proliferate in networks of …
functionally, normal germinal center B-cell growth. The tumor cells proliferate in networks of …
Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes
IS Lossos, AA Alizadeh, M Diehn… - Proceedings of the …, 2002 - National Acad Sciences
The natural history of follicular lymphoma (FL) is frequently characterized by transformation
to a more aggressive diffuse large B cell lymphoma (DLBCL). We compared the gene …
to a more aggressive diffuse large B cell lymphoma (DLBCL). We compared the gene …
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