Effect of smoking on methylation and semen parameters

N Naeimi, H Mohseni Kouchesfehani… - Environmental and …, 2024 - Wiley Online Library
One type of epigenetic modification is genomic DNA methylation, which is induced by
smoking, and both are associated with male infertility. In this study, the relationship between …

The status of global DNA methylation in the spermatozoa of smokers and non-smokers

MF Hamad, WAA Dayyih, M Laqqan, Y AlKhaled… - Reproductive …, 2018 - Elsevier
Research question Does regular smoking affect semen quality and the levels of DNA
methylation in mature human spermatozoa? Design Spermatozoa from 109 men were …

Cigarette heavy smoking alters DNA methylation patterns and gene transcription levels in humans spermatozoa

MM Laqqan, MM Yassin - Environmental Science and Pollution Research, 2022 - Springer
Tobacco smoking is considered the most common reason of death and infertility around the
world. This study was designed to assess the impact of tobacco heavy smoking on sperm …

Aberrant DNA methylation patterns of human spermatozoa in current smoker males

M Laqqan, S Tierling, Y Alkhaled, CL Porto… - Reproductive …, 2017 - Elsevier
The purpose of this study was to investigate the impact of current cigarette smoking on
sperm DNA methylation patterns. A total of 108 males (51 current smokers and 57 never …

[HTML][HTML] Potential effect of smoking on semen quality through DNA damage and the downregulation of Chk1 in sperm

X Cui, X Jing, X Wu, Z Wang… - Molecular Medicine …, 2016 - spandidos-publications.com
Previous studies have found that smoking is associated with decreased male fertility via
altering the quality of semen. However, the mechanism by which cigarette smoking affects …

[HTML][HTML] Association of Sperm Methylation at LINE-1, Four Candidate Genes, and Nicotine/Alcohol Exposure With the Risk of Infertility

W Zhang, M Li, F Sun, X Xu, Z Zhang, J Liu… - Frontiers in …, 2019 - frontiersin.org
In this study, we examined whether smoking and drinking affect sperm quality and the DNA
methylation of the repetitive element LINE-1, MEST, P16, H19, and GNAS in sperm. Semen …

[HTML][HTML] Influence of tobacco cigarette heavy smoking on DNA methylation patterns and transcription levels of MAPK8IP3, GAA, ANXA2, PRRC2A, and PDE11A …

MM Laqqan, MM Yassin - Middle East Fertility Society Journal, 2021 - Springer
Background Tobacco smoking is considered as one of the lifestyles factors that influence the
sperm DNA methylation and global sperm DNA methylation and that may affect the sperm …

[HTML][HTML] H19 gene methylation status is associated with male infertility

XP Li, CL Hao, Q Wang, XM Yi… - Experimental and …, 2016 - spandidos-publications.com
The present study investigated the H19 gene methylation status in male infertility. Between
March 2013 and June 2014, semen samples were collected from 15 normal fertile males …

Impact of cigarette‐smoking on sperm DNA methylation and its effect on sperm parameters

Y Alkhaled, M Laqqan, S Tierling, C Lo Porto… - Andrologia, 2018 - Wiley Online Library
DNA methylation is an epigenetic modification of the genome. The purpose of this study was
to determine the influence of cigarette‐smoking on sperm DNA methylation from a …

Cigarette smoking significantly alters sperm DNA methylation patterns

TG Jenkins, ER James, DF Alonso, JR Hoidal… - …, 2017 - Wiley Online Library
Numerous health consequences of tobacco smoke exposure have been characterized, and
the effects of smoking on traditional measures of male fertility are well described. However, a …