Crosstalk between microbiota, pathogens and the innate immune responses

C Guenther, C Josenhans, J Wehkamp - International Journal of Medical …, 2016 - Elsevier
Research in the last decade has convincingly demonstrated that the microbiota is crucial in
order to prime and orchestrate innate and adaptive immune responses of their host and …

Microbiota-stimulated immune mechanisms to maintain gut homeostasis

H Chung, DL Kasper - Current opinion in immunology, 2010 - Elsevier
In recent years there has been an explosion of interest to identify microbial inhabitants of
human and understand their beneficial role in health. In the gut, a symbiotic host–microbial …

Role of the gut microbiota in immunity and inflammatory disease

N Kamada, SU Seo, GY Chen, G Núñez - Nature Reviews Immunology, 2013 - nature.com
The mammalian intestine is colonized by trillions of microorganisms, most of which are
bacteria that have co-evolved with the host in a symbiotic relationship. The collection of …

Understanding immune–microbiota interactions in the intestine

PP Ahern, KJ Maloy - Immunology, 2020 - Wiley Online Library
The past two decades have seen an explosion in research that aims to understand how the
dynamic interplay with the gut microbiota impacts host health and disease, establishing a …

The effects of the microbiota on the host immune system

J Karczewski, B Poniedziałek, Z Adamski… - Autoimmunity, 2014 - Taylor & Francis
The human gastrointestinal track harbors hundreds of species of commensal organisms,
collectively known as microbiota. The composition of the intestinal microbiota is changeable …

Microbiota-mediated inflammation and antimicrobial defense in the intestine

S Caballero, EG Pamer - Annual review of immunology, 2015 - annualreviews.org
The diverse microbial populations constituting the intestinal microbiota promote immune
development and differentiation, but because of their complex metabolic requirements and …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

Immune–microbiota interactions in health and disease

NW Palm, MR de Zoete, RA Flavell - Clinical immunology, 2015 - Elsevier
Recent studies have revealed that the intestinal microbiota plays an important role in host
physiology and pathophysiology in health and disease. One of the major mechanisms by …

Deciphering the tête-à-tête between the microbiota and the immune system

NK Surana, DL Kasper - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
The past decade has witnessed an explosion in studies—both clinical and basic science—
examining the relationship between the microbiota and human health, and it is now clear …

Aspects of gut microbiota and immune system interactions in infectious diseases, immunopathology, and cancer

V Lazar, LM Ditu, GG Pircalabioru, I Gheorghe… - Frontiers in …, 2018 - frontiersin.org
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, bringing to the host organism a dowry of cells and genes more numerous …