Epigenetics is defined as the study of changes in gene function that are mitotically or
meiotically heritable and do not lead to a change in DNA sequence. Epigenetic …

After decades of research investment, techniques for the robust and efficient modification of
the chicken genome are now with us. The biology of the chicken has provided many …

The chicken embryo has been used as a classical embryological model for studying
developmental events because of its ready availability, similarity to the human embryos, and …

Background Environmental exposures, for instance to chemicals, are known to impact plant
and animal phenotypes on the long term, sometimes across several generations. Such …

Perinatal insults, including fetal undernutrition and hypoxia, are associated with an
increased susceptibility to several adult-onset metabolic disorders. These include …

The traditional strength of chicken embryos for studying development is that they are readily
manipulated. This has led to some major discoveries in developmental biology such as the …

A range of stresses experienced by the early embryo can alter the growth trajectory of the
fetus and neonate and creates a predisposition to a range of metabolic diseases after birth …

The chicken embryo has served as a classic model system for developmental studies due to
its easy access for surgical manipulations and a wealth of data about chicken …

In ovo electroporation is an excellent method to ectopically induce or inhibit gene
expression in chicken embryos and to study the in vivo function of genes during embryonic …

The chick embryo has a long and distinguished history as a major model system in
developmental biology and has also contributed major concepts to immunology, genetics …