Antimicrobial peptides are host-encoded antibiotics that combat invading microbes and help
shape the microbiome in plants and animals. However, little is known about how the host …

Antimicrobial peptides are host-encoded immune effectors that combat pathogens and
shape the microbiome in plants and animals. However, little is known about how the host …

The innate immune system provides hosts with a crucial first line of defense against
pathogens. While immune genes are often among the fastest evolving genes in the genome …

There is a developing interest in how immune genes may function in other physiological
roles, and how traditionally non-immune peptides may, in fact, be active in immune contexts …

Engineering new functions in the microbiome requires understanding how host genetic
control and microbe–microbe interactions shape the microbiome. One key genetic …

The innate immune system, present in various species, functions as the primary barrier
against pathogens, preventing infection and maintaining homeostasis. It consists of …

Host-associated microbiomes influence their host's fitness in myriad ways and can be
viewed as a source of phenotypic plasticity. This plasticity may allow the host to …

The evolution of host immunity occurs in the context of the microbiome, but little theory exists
to predict how resistance against pathogens might be influenced by the need to tolerate and …

Pathogens newly invading a host must compete with resident microbiota. This within-host
microbial warfare could lead to more severe disease outcomes or constrain the evolution of …

The microbiome shapes many traits in hosts, but we still do not understand how it influences
host evolution. To impact host evolution, the microbiome must be heritable and have …