Evidence for the involvement of JAK/STAT/SOCS pathway in the mechanism of Tangshen formula-treated diabetic nephropathy

J Hu, X Fan, X Meng, Y Wang, Q Liang, G Luo - Planta medica, 2014 - thieme-connect.com
Diabetic nephropathy is one of the most significant microvascular complications associated
with diabetes. Until now, there is no effective treatment and the gene mechanism of diabetic …

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

IMWA Putra, N Fakhrudin, A Nurrochmad, S Wahyuono - Life, 2023 - mdpi.com
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …

Akebia Saponin D ameliorated kidney injury and exerted anti-inflammatory and anti-apoptotic effects in diabetic nephropathy by activation of NRF2/HO-1 and …

C Lu, G Fan, D Wang - International Immunopharmacology, 2020 - Elsevier
Diabetic nephropathy (DN), a common microvascular complication of type 2 diabetes
mellitus (T2DM), causes increasing mortality and morbidity due to its high prevalence and …

Tang‐Tong‐Fang Confers Protection against Experimental Diabetic Peripheral Neuropathy by Reducing Inflammation

M Li, D Huang, X Liu, L Lin - Evidence‐Based Complementary …, 2015 - Wiley Online Library
Tang‐tong‐fang (TTF) is a Chinese herbal formula that has been shown to be beneficial in
diabetic peripheral neuropathy (DPN), a common complication secondary to diabetic …

Cissus quadrangularis extract attenuates diabetic nephropathy by altering SIRT1/DNMT1 axis

AA Syed, MI Reza, R Garg, UK Goand… - Journal of Pharmacy …, 2021 - academic.oup.com
Abstract Objectives Hyperglycemia-induced SIRT1, DNMT1, SODs, as well as oxidative
stress, play a pivotal role in the progression of diabetic nephropathy. Cissus quadrangularis …

Tannins and vascular complications of Diabetes: An update

AP Laddha, YA Kulkarni - Phytomedicine, 2019 - Elsevier
Background Diabetes mellitus is a chronic metabolic disorder associated with persistent
increased level of glucose in the blood. According to a report by World Health Organisation …

Effect and Mechanisms of Huangqi-Shanzhuyu in the Treatment of Diabetic Nephropathy based on Network Pharmacology and In Vitro Experiments

Y Han, S Wei, C Liu, Y Nie, S Yuan… - … Chemistry & High …, 2024 - ingentaconnect.com
Background: Huangqi-Shanzhuyu (HS), a classic combination of Chinese herbal formulae,
has been widely used for the treatment of diabetic nephropathy (DN). However, its …

Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic …

Y Ma, Y Deng, N Li, A Dong, H Li, S Chen… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Diabetic nephropathy (DN) is one of the most common
and serious microvascular complications of Diabetes mellitus (DM). The inflammatory …

Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway

F Liu, Q Feng, M Yang, Y Yang, J Nie… - Phytotherapy …, 2024 - Wiley Online Library
Diabetic nephropathy (DN) is the most common and serious complication of diabetes,
posing a significant threat to human health. Currently, safe and effective preventive …

Unveiling Anti-Diabetic Potential of Baicalin and Baicalein from Baikal Skullcap: LC–MS, In Silico, and In Vitro Studies

W Zhao, H Cui, K Liu, X Yang, S Xing, W Li - International Journal of …, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is marked by persistent hyperglycemia, insulin resistance,
and pancreatic β-cell dysfunction, imposing substantial health burdens and elevating the …